DNA Binding Motif

						

			
Accessions: UP00371A_2 (UniPROBE 20160601), UP00384A_9 (UniPROBE 20160601)

			
Names: C02B8.4, CeTwist, Helix-loop-helix protein 8, HLH-2_HLH-8, Twist-related protein
Organisms: Caenorhabditis elegans
Libraries: UniPROBE 20160601 1
1 Hume MA, Barrera LA, Gisselbrecht SS, Bulyk ML. UniPROBE, update 2015: new tools and content for the online database of protein-binding microarray data on protein-DNA interactions. Nucleic Acids Res : (2015). [Pubmed]
Length: 16
Consensus: aymaACATmTGGtwkm
Weblogo: 
PSSM: P0      A      C      G      T
01   0.33   0.21   0.23   0.23      a
02   0.14   0.30   0.22   0.33      y
03   0.40   0.29   0.18   0.14      m
04   0.64   0.17   0.11   0.08      a
05   0.77   0.16   0.05   0.01      A
06   0.03   0.95   0.01   0.01      C
07   0.97   0.01   0.01   0.01      A
08   0.01   0.06   0.06   0.88      T
09   0.36   0.57   0.07      0      m
10   0.02   0.01   0.01   0.96      T
11   0.01   0.02   0.96   0.02      G
12   0.01   0.03   0.78   0.18      G
13   0.13   0.22   0.08   0.57      t
14   0.29   0.19   0.24   0.28      w
15   0.15   0.18   0.26   0.41      k
16   0.29   0.39   0.14   0.18      m
Type: Heterodimer
Binding TFs: UP00371A (Helix-loop-helix DNA-binding domain)
UP00384A (Helix-loop-helix DNA-binding domain)
Binding Sites: AACAGATG
AACATATG
AACATCTG
AACATGTG
ACAGATGT
ACATATGG
ACATATGT
ACATCTGG
ACATGTGG
ACCACATG
ACCAGATG
ACCATATG
CACATCTG
CACATGTG
CATATGGA
CATATGGC
CATATGGG
CATATGTC
CCATATGC
CCATATGG
			
Publications: Grove C.A, De Masi F, Barrasa M.I, Newburger D.E, Alkema M.J, Bulyk M.L, Walhout A.J. A multiparameter network reveals extensive divergence between C. elegans bHLH transcription factors. Cell 138:314-27 (2009). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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