DNA Binding Motif

						

			
Accessions: UP00548C_1 (UniPROBE 20160601)

			
Names: Helix Loop Helix Protein 1, HLH-1_L13T, MyoD1
Organisms: Caenorhabditis elegans
Libraries: UniPROBE 20160601 1
1 Hume MA, Barrera LA, Gisselbrecht SS, Bulyk ML. UniPROBE, update 2015: new tools and content for the online database of protein-binding microarray data on protein-DNA interactions. Nucleic Acids Res : (2015). [Pubmed]
Length: 23
Consensus: rywgggRACAGCTGtyyksracm
Weblogo: 
PSSM: P0      A      C      G      T
01   0.32   0.15   0.29   0.24      r
02   0.24   0.28   0.22   0.26      y
03   0.40   0.19   0.16   0.25      w
04   0.17   0.19   0.40   0.25      g
05   0.22   0.24   0.31   0.23      g
06   0.17   0.22   0.43   0.19      g
07   0.68   0.03   0.27   0.02      R
08   0.80   0.02   0.09   0.09      A
09   0.01   0.97   0.01   0.01      C
10   0.96      0   0.01   0.03      A
11   0.03   0.08   0.80   0.09      G
12   0.13   0.71   0.16   0.01      C
13   0.03   0.01   0.01   0.96      T
14   0.01   0.01   0.97   0.01      G
15   0.20   0.14   0.05   0.61      t
16   0.02   0.63   0.02   0.33      y
17   0.23   0.27   0.20   0.31      y
18   0.23   0.24   0.27   0.26      k
19   0.18   0.40   0.25   0.17      s
20   0.37   0.21   0.30   0.12      r
21   0.36   0.25   0.20   0.20      a
22   0.24   0.38   0.18   0.19      c
23   0.26   0.36   0.19   0.19      m
Binding TFs: UP00548C (Helix-loop-helix DNA-binding domain)
Binding Sites: AACACGTG
AACAGCTG
AACATATG
ACACGTGC
ACACGTGT
ACAGCTGT
AGCACGTG
CACACGTG
CACGTGTC
CAGCTGAC
CAGCTGTC
GCATATGC
AACACATG
AACATGTG
ACACATGT
ACAGATGT
ACATATGT
CACATGTC
CACATGTG
CATATGTC
			
Publications: De Masi F, Grove CA, Vedenko A, Alibés A, Gisselbrecht SS, Serrano L, Bulyk ML, Walhout AJ. Using a structural and logics systems approach to infer bHLH-DNA binding specificity determinants. Nucleic Acids Res 39:4553-63 (2011). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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