Transcription Factor
| Accessions: | UP00381A (UniPROBE 20160601) |
| Names: | Abnormal cell lineage protein 32, hlh-7, LIN-32, Protein lin-32, T14F9.5 |
| Organisms: | Caenorhabditis elegans |
| Libraries: | UniPROBE 20160601 1 1 Hume MA, Barrera LA, Gisselbrecht SS, Bulyk ML. UniPROBE, update 2015: new tools and content for the online database of protein-binding microarray data on protein-DNA interactions. Nucleic Acids Res : (2015). [Pubmed] |
| Uniprot: | Q10574 |
| Description: | abnormal cell LINeage: lin-32 encodes a basic helix-loop-helix transcription factor that is required for development of several types of neurons, including the touch receptor neurons and the male sensory ray neurons. |
| Length: | 70 |
| Pfam Domains: | 1-52 Helix-loop-helix DNA-binding domain |
| Sequence: (in bold interface residues) | 1 RRSAANERERRRMNTLNVAYDELREVLPEIDSGKKLSKFETLQMAQKYIECLSQILKQDS 60 61 KNENLKSKSG |
| Interface Residues: | 2, 4, 5, 6, 8, 9, 12, 13, 34, 38 |
| 3D-footprint Homologues: | 7z5k_B, 2ypa_A, 1an4_A, 5i50_B, 1am9_A, 4h10_A, 7ssa_L, 5eyo_A, 2ql2_D, 8osl_P, 5gnj_I |
| Binding Motifs: | UP00381A_1 akwraTwagwaswm UP00381A_2 hmgamCAgcTGkymtc |
| Binding Sites: | AACAGATG AACAGCTG AACAGGTG ACACCTGT ACAGCTGG ACAGCTGT ACCACCTG CAGCTGTC AACATCTG ACAGATGG ACAGATGT ACAGGTGG ACATATGG ACATCTGG ACCAGATG ACCATCTG CAGATGGC CATCTGTC CCAGATGG CCATATGG |
| Publications: | Grove C.A, De Masi F, Barrasa M.I, Newburger D.E, Alkema M.J, Bulyk M.L, Walhout A.J. A multiparameter network reveals extensive divergence between C. elegans bHLH transcription factors. Cell 138:314-27 (2009). [Pubmed] |
| Related annotations: | PaperBLAST |
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