Transcription Factor
| Accessions: | UP00381A (UniPROBE 20160601) |
| Names: | Abnormal cell lineage protein 32, hlh-7, LIN-32, Protein lin-32, T14F9.5 |
| Organisms: | Caenorhabditis elegans |
| Libraries: | UniPROBE 20160601 1 1 Hume MA, Barrera LA, Gisselbrecht SS, Bulyk ML. UniPROBE, update 2015: new tools and content for the online database of protein-binding microarray data on protein-DNA interactions. Nucleic Acids Res : (2015). [Pubmed] |
| Uniprot: | Q10574 |
| Description: | abnormal cell LINeage: lin-32 encodes a basic helix-loop-helix transcription factor that is required for development of several types of neurons, including the touch receptor neurons and the male sensory ray neurons. |
| Length: | 70 |
| Pfam Domains: | 1-52 Helix-loop-helix DNA-binding domain |
| Sequence: (in bold interface residues) | 1 RRSAANERERRRMNTLNVAYDELREVLPEIDSGKKLSKFETLQMAQKYIECLSQILKQDS 60 61 KNENLKSKSG |
| Interface Residues: | 2, 4, 5, 6, 8, 9, 12, 13, 34, 38 |
| 3D-footprint Homologues: | 2ypa_A, 7z5k_B, 1an4_A, 5i50_B, 1am9_A, 4h10_A, 7ssa_L, 5eyo_A, 2ql2_D, 8osl_P, 5gnj_I |
| Binding Motifs: | UP00381A_1 akwraTwagwaswm UP00381A_2 hmgamCAgcTGkymtc |
| Binding Sites: | AACAGATG AACAGCTG AACAGGTG ACACCTGT ACAGCTGG ACAGCTGT ACCACCTG CAGCTGTC AACATCTG ACAGATGG ACAGATGT ACAGGTGG ACATATGG ACATCTGG ACCAGATG ACCATCTG CAGATGGC CATCTGTC CCAGATGG CCATATGG |
| Publications: | Grove C.A, De Masi F, Barrasa M.I, Newburger D.E, Alkema M.J, Bulyk M.L, Walhout A.J. A multiparameter network reveals extensive divergence between C. elegans bHLH transcription factors. Cell 138:314-27 (2009). [Pubmed] |
| Related annotations: | PaperBLAST |
Disclaimer and license
These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.