DNA Binding Site
| Accessions: | TATAAACA (UniPROBE 20160601), MA0047.4.8 (JASPAR 2024) |
| Organisms: | Mus musculus, Saccharomyces cerevisiae, Allomyces macrogynus, Drosophila melanogaster, Homo sapiens |
| Libraries: | UniPROBE 20160601 1, JASPAR 2024 2 1 Hume MA, Barrera LA, Gisselbrecht SS, Bulyk ML. UniPROBE, update 2015: new tools and content for the online database of protein-binding microarray data on protein-DNA interactions. Nucleic Acids Res : (2015). [Pubmed] 2 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed] |
| Length: | 8 |
| Sequence: | TATAAACA |
| Type: | Heterodimer |
| Binding TFs: | UP00353A (Fork head domain, FHA domain) Q9Y261 (Fork head domain, Forkhead N-terminal region, HNF3 C-terminal domain) UP00025A (Fork head domain) UP00039A (Fork head domain) UP00061A (Fork head domain) UP00312A (Fork head domain, FHA domain) UP00515A (Fork head domain) UP00520A (Fork head domain) UP00589A (Fork head domain) UP00589B (Fork head domain) UP00589G (Fork head domain) UP00604E (Homeobox domain) Q9Y261 |
| Binding Motifs: | UP00025A_1 wraAtGTAAACAAavrb UP00039A_1 hraarRTAAACAAwsmc UP00061A_1 wwwatrTAAACAAwsrb UP00312A_1 tdwaawGTAAACAAAgrkrv UP00353A_1 yrwwwtGTAAACAAarrrgr UP00025A_2 cwaAymAyAACAhmy UP00039A_2 awbrcCmwAACAwwksw UP00061A_2 awatyawAACAAmamm UP00515A_1 wmrbtrtGatTGTTTAtcwtwhm UP00515A_2 symmsagmmhAyAACAwwkggyk UP00520A_1 wwwtawgrTAAACAAwyktgtk UP00520A_2 mbbamtrAtGACGCcAmkkmacy UP00589A_1 wkagkywAwrTAAAyAwagrgrk UP00589B_1 rawscwTAwrTAAACAaTawka UP00589G_1 bmavkdwAtrTAAACAAwsrkdk UP00604E_1 tawwywATrTwwATtAwytaAA MA0047.4 wGTAAACA |
| Publications: | Badis G, Berger M.F, Philippakis A.A, Talukder S, Gehrke A.R, Jaeger S.A, Chan E.T, Metzler G, Vedenko A, Chen X, Kuznetsov H, Wang C.F, Coburn D, Newburger D.E, Morris Q, Hughes T.R, Bulyk M.L. Diversity and complexity in DNA recognition by transcription factors. Science (New York, N.Y.) 324:1720-3 (2009). [Pubmed] Li J, Dantas Machado AC, Guo M, Sagendorf JM, Zhou Z, Jiang L, Chen X, Wu D, Qu L, Chen Z, Chen L, Rohs R, Chen Y. Structure of the Forkhead Domain of FOXA2 Bound to a Complete DNA Consensus Site. Biochemistry 56:3745-3753 (2017). [Pubmed] |
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