Transcription Factor
| Accessions: | UP00312A (UniPROBE 20160601) |
| Names: | "Fork head protein homolog 2, Fkh2, N2403, YNL068C, YNL2403C" |
| Organisms: | Saccharomyces cerevisiae |
| Libraries: | UniPROBE 20160601 1 1 Hume MA, Barrera LA, Gisselbrecht SS, Bulyk ML. UniPROBE, update 2015: new tools and content for the online database of protein-binding microarray data on protein-DNA interactions. Nucleic Acids Res : (2015). [Pubmed] |
| Uniprot: | P41813 |
| Description: | Transcription factor of the forkhead family that regulates the cell cycle and pseudohyphal growth; also involved in chromatin silencing at HML and HMR; potential Cdc28p substrate |
| Length: | 386 |
| Pfam Domains: | 17-105 FHA domain 273-367 Fork head domain |
| Sequence: (in bold interface residues) | 1 MLSGPNWTYYVKDLEVSIGRNTDPLNSALQENSDGVKNSYRVNIDLGPAKVVSRKHAIIK 60 61 YNMNIGGWELHILGRNGAKVNFQRTHNGPNNPPIRLSSGTLLDIGGTQMMFILPDSDPVV 120 121 APICIEHLMPNLINMFGLEGNNNPLLRDIIKQSNYAKQRQLTSNQQIKGFKLYGSGGNAP 180 181 FGSGANLGPSEQGIFNNNNNSKNKNGYFTSINPNYTASTTTSNTINPQAASPQGPPNTII 240 241 AANFVDSYKSSNAYPQALDFTSDLSHDENRNVKPPHSYATMITQAILSSPEGVISLADIY 300 301 KYISSNYAYYRFAKSGWQNSIRHNLSLNKAFEKVPRRPNEPGKGMKWRISESYQQEFLNK 360 361 WNTGKVGKIRRGSSVARQLQLHMAKF |
| Interface Residues: | 270, 313, 316, 318, 319, 320, 322, 323, 324, 326, 327, 336, 343 |
| 3D-footprint Homologues: | 7yz7_A, 7yzb_A, 3l2c_A, 7vox_H, 2hdc_A, 7yzg_A, 7tdw_A, 3g73_A, 6el8_A, 7tdx_A, 6nce_A, 2uzk_A, 7vou_C, 2a07_J, 7yze_A, 7cby_C, 3co6_C, 6ako_C, 2c6y_A, 3qrf_G |
| Binding Motifs: | UP00312A_1 tdwaawGTAAACAAAgrkrv |
| Binding Sites: | GTAAACAA AATAAACA AGTAAACA AGTAAATA ATAAACAA ATAAACAC ATGTTTAC CGTAAACA CTATTTAC CTGTTTAC GATAAACA GGTAAACA GTAAACAC GTAAATAA TAAACAAA TAAACACA TATAAACA TATTTACA TGTAAACA ATAAACAG |
| Publications: | *Zhu C, *Byers K, *McCord RP, Shi Z, Berger MF, Newburger D, Saulrieta K, Smith Z, Shah M, Radhakrishnan M, Philippakis AA, Hu Y, De Masi F, Pacek M, Rolfs A , Murthy TVS, LaBaer J, Bulyk ML. High-Resolution DNA Binding Specificity Analysis of Yeast Transcription Factors. Genome Research. Epub January 21, 2009, doi:10.1101/gr.090233.108 (*co-1st authors). [Pubmed] |
| Related annotations: | PaperBLAST |
Disclaimer and license
These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.