Transcription Factor
| Accessions: | Foxk1_DBD (HumanTF 1.0), UP00025A (UniPROBE 20160601) |
| Names: | Foxk1, Foxk1 protein, Fragment, Q99LQ5_MOUSE, A630048H08Rik, AI463295, C330006K01Rik, forkhead box K1, Forkhead box protein K1, Mnf, Myocyte nuclear factor |
| Organisms: | Mus musculus |
| Libraries: | HumanTF 1.0 1, UniPROBE 20160601 2 1 Jolma A, Yan J, Whitington T, Toivonen J, Nitta KR, Rastas P, Morgunova E, Enge M, Taipale M, Wei G, Palin K, Vaquerizas JM, Vincentelli R, Luscombe NM, Hughes TR, Lemaire P, Ukkonen E, Kivioja T, Taipale J. DNA-Binding Specificities of Human Transcription Factors. Cell. 2013 Jan 17;152(1-2):327-39. [Pubmed] 2 Hume MA, Barrera LA, Gisselbrecht SS, Bulyk ML. UniPROBE, update 2015: new tools and content for the online database of protein-binding microarray data on protein-DNA interactions. Nucleic Acids Res : (2015). [Pubmed] |
| Uniprot: | P42128 |
| Description: | forkhead box K1: Mus musculus forkhead box K1 (Foxk1), transcript variant 1, mRNA. |
| Notes: | Ensembl ID: ENSMUSG00000056493; DNA-binding domain sequence; TF family: Forkhead; Clone source: Hughes lab. |
| Length: | 128 |
| Pfam Domains: | 18-113 Fork head domain |
| Sequence: (in bold interface residues) | 1 SEQQADASGGDSPKDESKPPYSYAQLIVQAISSAQDRQLTLSGIYAHITKHYPYYRTADK 60 61 GWQNSIRHNLSLNRYFIKVPRSQEEPGKGSFWRIDPASEAKLVEQAFRKRRQRGVSCFRT 120 121 PFGPLSSR |
| Interface Residues: | 58, 61, 63, 64, 65, 67, 68, 69, 71, 72, 81, 88, 113 |
| 3D-footprint Homologues: | 3l2c_A, 7vox_H, 2hdc_A, 7yzb_A, 6nce_A, 2uzk_A, 7vou_C, 2a07_J, 7yze_A, 7cby_C, 3co6_C, 6ako_C, 2c6y_A, 7yzg_A, 7tdw_A, 3g73_A, 7yz7_A, 6el8_A, 7tdx_A, 3qrf_G |
| Binding Motifs: | UP00025A_1 wraAtGTAAACAAavrb Foxk1_DBD_1 CGGACACAATC Foxk1_DBD_2 rTAAACA UP00025A_2 cwaAymAyAACAhmy |
| Binding Sites: | GTAAACAA AATAAACA AGTAAACA ATAAACAA ATAAACAT ATGTTTAC CATAAACA CGTAAACA CTGTTTAC GATAAACA GGTAAACA GTAAACAC GTAAATAA GTCAACAA TAAACAAA TAAACATA TATAAACA TATTTACA TGTAAACA TGTCAACA |
| Publications: | Jolma A, Yan J, Whitington T, Toivonen J, Nitta KR, Rastas P, Morgunova E, Enge M, Taipale M, Wei G, Palin K, Vaquerizas JM, Vincentelli R, Luscombe NM, Hughes TR, Lemaire P, Ukkonen E, Kivioja T, Taipale J. DNA-Binding Specificities of Human Transcription Factors. Cell. 2013 Jan 17;152(1-2):327-39. [Pubmed] Badis G, Berger M.F, Philippakis A.A, Talukder S, Gehrke A.R, Jaeger S.A, Chan E.T, Metzler G, Vedenko A, Chen X, Kuznetsov H, Wang C.F, Coburn D, Newburger D.E, Morris Q, Hughes T.R, Bulyk M.L. Diversity and complexity in DNA recognition by transcription factors. Science (New York, N.Y.) 324:1720-3 (2009). [Pubmed] |
| Related annotations: | PaperBLAST |
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