DNA Binding Site
| Accessions: | TGTCAACA (UniPROBE 20160601), MA0047.4.1 (JASPAR 2024), MA2320.1.5 (JASPAR 2024) |
| Organisms: | Mus musculus, Plasmodium falciparum, Homo sapiens, Drosophila melanogaster |
| Libraries: | UniPROBE 20160601 1, JASPAR 2024 2 1 Hume MA, Barrera LA, Gisselbrecht SS, Bulyk ML. UniPROBE, update 2015: new tools and content for the online database of protein-binding microarray data on protein-DNA interactions. Nucleic Acids Res : (2015). [Pubmed] 2 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed] |
| Length: | 8 |
| Sequence: | TGTCAACA |
| Type: | Heterodimer |
| Binding TFs: | Q9Y261 (Fork head domain, Forkhead N-terminal region, HNF3 C-terminal domain) UP00025A (Fork head domain) UP00073A (Fork head domain, Forkhead N-terminal region) UP00440A (AP2 domain) Q9VA17 Q9Y261 |
| Binding Motifs: | UP00025A_1 wraAtGTAAACAAavrb UP00073A_1 wawawGTAAAyAAwvab UP00025A_2 cwaAymAyAACAhmy UP00073A_2 rrwaaTAACAaasgs UP00440A_1 ChwysmdTGACATCAwrmrwag MA0047.4 wGTAAACA MA2320.1 TGTTAACA |
| Publications: | Badis G, Berger M.F, Philippakis A.A, Talukder S, Gehrke A.R, Jaeger S.A, Chan E.T, Metzler G, Vedenko A, Chen X, Kuznetsov H, Wang C.F, Coburn D, Newburger D.E, Morris Q, Hughes T.R, Bulyk M.L. Diversity and complexity in DNA recognition by transcription factors. Science (New York, N.Y.) 324:1720-3 (2009). [Pubmed] Li J, Dantas Machado AC, Guo M, Sagendorf JM, Zhou Z, Jiang L, Chen X, Wu D, Qu L, Chen Z, Chen L, Rohs R, Chen Y. Structure of the Forkhead Domain of FOXA2 Bound to a Complete DNA Consensus Site. Biochemistry 56:3745-3753 (2017). [Pubmed] Contreras EG, Palominos T, Glavic A, Brand AH, Sierralta J, Oliva C. The transcription factor SoxD controls neuronal guidance in the Drosophila visual system. Sci Rep 8:13332 (2018). [Pubmed] |
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