DNA Binding Motif

Accessions: MA0047.4 (JASPAR 2024)
Names: FOXA2
Organisms: Homo sapiens
Libraries: JASPAR 2024 1
1 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed]
Notes: ChIP-seq
Length: 8
Consensus: wGTAAACA
Weblogo:
PSSM: P0 A C G T
01 93740 12432 38538 117443 w
02 18770 2928 236311 4144 G
03 3737 2037 1890 254489 T
04 243805 9424 2641 6283 A
05 223061 22429 6484 10179 A
06 248214 3329 2805 7805 A
07 2411 196969 3603 59170 C
08 246665 3086 2984 9418 A
Type: Heterodimer
Binding TFs: Q9Y261 (Fork head domain, Forkhead N-terminal region, HNF3 C-terminal domain)
Q9Y261
Binding Sites: MA0047.4.17 / MA0047.4.19
MA0047.4.14
MA0047.4.15
MA0047.4.8
MA0047.4.4 / MA0047.4.9
MA0047.4.1
MA0047.4.7
MA0047.4.3
MA0047.4.2 / MA0047.4.5 / MA0047.4.6
MA0047.4.10 / MA0047.4.18
MA0047.4.11
MA0047.4.12
MA0047.4.13
MA0047.4.16
MA0047.4.20
Publications: Li J, Dantas Machado AC, Guo M, Sagendorf JM, Zhou Z, Jiang L, Chen X, Wu D, Qu L, Chen Z, Chen L, Rohs R, Chen Y. Structure of the Forkhead Domain of FOXA2 Bound to a Complete DNA Consensus Site. Biochemistry 56:3745-3753 (2017). [Pubmed]

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