DNA Binding Motif

						

			
Accessions: UP00073A_1 (UniPROBE 20160601)

			
Names: forkhead box A2, Forkhead box protein A2, Foxa2, Hepatocyte nuclear factor 3-beta, Hnf-3b, HNF3-beta, Hnf3b, HNF3beta, Tcf-3b, Tcf3b
Organisms: Mus musculus
Libraries: UniPROBE 20160601 1
1 Hume MA, Barrera LA, Gisselbrecht SS, Bulyk ML. UniPROBE, update 2015: new tools and content for the online database of protein-binding microarray data on protein-DNA interactions. Nucleic Acids Res : (2015). [Pubmed]
Length: 17
Consensus: wawawGTAAAyAAwvab
Weblogo: 
PSSM: P0      A      C      G      T
01   0.34   0.21   0.13   0.33      w
02   0.41   0.18   0.18   0.23      a
03   0.41   0.13   0.09   0.37      w
04   0.61   0.08   0.11   0.21      a
05   0.43   0.04   0.15   0.38      w
06   0.09   0.01   0.89   0.01      G
07      0   0.04      0   0.96      T
08   0.92   0.07      0   0.01      A
09   0.92   0.07      0   0.01      A
10   0.99      0      0   0.01      A
11      0   0.66      0   0.34      y
12   0.99      0      0   0.01      A
13   0.72   0.07   0.05   0.16      A
14   0.54   0.10   0.10   0.26      w
15   0.25   0.27   0.30   0.18      v
16   0.31   0.21   0.25   0.24      a
17   0.22   0.28   0.25   0.25      b
Binding TFs: UP00073A (Fork head domain, Forkhead N-terminal region)
Binding Sites: AATAAACA
AGTAAACA
AGTAAATA
ATAAACAA
ATATTTAC
ATGTTTAC
CTATTTAC
CTGTTTAC
GGTAAACA
GGTAAATA
GTAAACAC
GTAAATAA
GTACACAA
GTCAACAA
TAAACAAA
TAAATAAA
TATTGACA
TATTTACA
TGTAAACA
TGTCAACA
			
Publications: Badis G, Berger M.F, Philippakis A.A, Talukder S, Gehrke A.R, Jaeger S.A, Chan E.T, Metzler G, Vedenko A, Chen X, Kuznetsov H, Wang C.F, Coburn D, Newburger D.E, Morris Q, Hughes T.R, Bulyk M.L. Diversity and complexity in DNA recognition by transcription factors. Science (New York, N.Y.) 324:1720-3 (2009). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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