Transcription Factor

Accessions: UP00520A (UniPROBE 20160601)
Names: Checkpoint suppressor homologue, CHES-1-like
Organisms: Drosophila melanogaster
Libraries: UniPROBE 20160601 1
1 Hume MA, Barrera LA, Gisselbrecht SS, Bulyk ML. UniPROBE, update 2015: new tools and content for the online database of protein-binding microarray data on protein-DNA interactions. Nucleic Acids Res : (2015). [Pubmed]
Length: 131
Pfam Domains: 23-109 Fork head domain
Sequence:
(in bold interface residues)
1 NTPQKQKHPNNVPYDPLVHTNNKPPYSFSSLIFMAIEGSNEKALPVKEIYAWIVQHFPYF 60
61 KTAPNGWKNSVRHNLSLNKSFVKVEKAPNMGKGSLWRVEPQQRQNLIQALNRSPFFPNSA 120
121 VDKISPSLKSP
Interface Residues: 66, 68, 69, 70, 72, 73, 74, 76, 77, 86, 92
3D-footprint Homologues: 7vox_H, 2hdc_A, 7yzg_A, 7tdw_A, 3g73_A, 7yz7_A, 6el8_A, 7tdx_A, 3l2c_A, 7yzb_A, 6nce_A, 2uzk_A, 7vou_C, 2a07_J, 7yze_A, 7cby_C, 3co6_C, 6ako_C, 2c6y_A, 3qrf_G
Binding Motifs: UP00520A_1 wwwtawgrTAAACAAwyktgtk
UP00520A_2 mbbamtrAtGACGCcAmkkmacy
Binding Sites: GTAAACAA
ATAAACAA
ATTGTTTA
GTTGTTTA
TAAACAAA
TATAAACA
TGTATACA
AAAGCGTC
AAGACGCG
AAGCGTCC
AGACGCTA
AGGACGCC
ATAGCGTC
ATGGCGTC
CGACGCTA
GACGCCAA
GACGCTAA
GAGACGCC
GGACGCCA
GGACGCTA
Publications: Nakagawa S, Gisselbrecht SS, Rogers JM, Hartl DL, Bulyk ML. DNA-binding specificity changes in the evolution of forkhead transcription factors. Proc Natl Acad Sci U S A 110:12349-54 (2013). [Pubmed]
Related annotations: PaperBLAST

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These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.