Transcription Factor

Accessions: UP00061A (UniPROBE 20160601)
Names: fkh-6, fkh6, Fkhl11, forkhead box L1, Forkhead box protein L1, Forkhead-related protein FKHL11, Foxl1, FREAC7, Transcription factor FKH-6
Organisms: Mus musculus
Libraries: UniPROBE 20160601 1
1 Hume MA, Barrera LA, Gisselbrecht SS, Bulyk ML. UniPROBE, update 2015: new tools and content for the online database of protein-binding microarray data on protein-DNA interactions. Nucleic Acids Res : (2015). [Pubmed]
Uniprot: Q64731
Description: forkhead box L1: M.musculus fkh-6 gene
Length: 128
Pfam Domains: 18-112 Fork head domain
Sequence:
(in bold interface residues)
1 FAPAAALAGPGRVEPPQKPPYSYIALIAMAIQDAPEQRVTLNGIYQFIMDRFPFYHDNRQ 60
61 GWQNSIRHNLSLNECFVKVPREKGRPGKGSYWTLDPRCLDMFENGNYRRRKRKPKPAAGS 120
121 PEAKRTRV
Interface Residues: 58, 61, 63, 64, 65, 67, 68, 69, 71, 72, 81, 88, 113
3D-footprint Homologues: 3l2c_A, 7vox_H, 2hdc_A, 7yzg_A, 7tdw_A, 3g73_A, 7yz7_A, 6el8_A, 7tdx_A, 7yzb_A, 6nce_A, 2uzk_A, 7vou_C, 2a07_J, 7yze_A, 7cby_C, 3co6_C, 6ako_C, 2c6y_A, 3qrf_G
Binding Motifs: UP00061A_1 wwwatrTAAACAAwsrb
UP00061A_2 awatyawAACAAmamm
Binding Sites: GTAAACAA
AATAAACA
AATGTTTA
AGTAAACA
AGTAAATA
ATAAACAT
ATGTTTAC
ATTGTTTA
CATAAACA
CGTAAACA
GATAAACA
GTAAACAC
GTAAATAA
GTTGTTTA
TAAACAAA
TAAACATA
TAAATAAA
TATAAACA
TATTTACA
TGTAAACA
Publications: Badis G, Berger M.F, Philippakis A.A, Talukder S, Gehrke A.R, Jaeger S.A, Chan E.T, Metzler G, Vedenko A, Chen X, Kuznetsov H, Wang C.F, Coburn D, Newburger D.E, Morris Q, Hughes T.R, Bulyk M.L. Diversity and complexity in DNA recognition by transcription factors. Science (New York, N.Y.) 324:1720-3 (2009). [Pubmed]
Related annotations: PaperBLAST

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