Transcription Factor

Accessions: Foxj3_DBD (HumanTF 1.0), UP00039A (UniPROBE 20160601)
Names: Foxj3, FOXJ3_MOUSE, C330039G02Rik, DKFZp761E2211, forkhead box J3, Forkhead box protein J3, Kiaa1041, mKIAA1041
Organisms: Mus musculus
Libraries: HumanTF 1.0 1, UniPROBE 20160601 2
1 Jolma A, Yan J, Whitington T, Toivonen J, Nitta KR, Rastas P, Morgunova E, Enge M, Taipale M, Wei G, Palin K, Vaquerizas JM, Vincentelli R, Luscombe NM, Hughes TR, Lemaire P, Ukkonen E, Kivioja T, Taipale J. DNA-Binding Specificities of Human Transcription Factors. Cell. 2013 Jan 17;152(1-2):327-39. [Pubmed]
2 Hume MA, Barrera LA, Gisselbrecht SS, Bulyk ML. UniPROBE, update 2015: new tools and content for the online database of protein-binding microarray data on protein-DNA interactions. Nucleic Acids Res : (2015). [Pubmed]
Uniprot: Q8BUR3
Description: forkhead box J3: Mus musculus similar to Putative forkhead box protein KIAA1041 (LOC230700), mRNA
Notes: Ensembl ID: ENSMUSG00000032998; DNA-binding domain sequence; TF family: Forkhead; Clone source: Hughes lab.
Length: 132
Pfam Domains: 18-102 Fork head domain
Sequence:
(in bold interface residues)
1 DPNTTLDQEEVQQHKDGKPPYSYASLITFAINSSPKKKMTLSEIYQWICDNFPYYREAGS 60
61 GWKNSIRHNLSLNKCFLKVPRSKDDPGKGSYWAIDTNPKEDTLPTRPKKRARSVERASTP 120
121 YSIDSDSLGMEC
Interface Residues: 15, 61, 63, 64, 65, 67, 68, 69, 71, 72, 75, 77, 78, 81, 88, 109
3D-footprint Homologues: 7yzb_A, 7vox_H, 2hdc_A, 7yze_A, 7cby_C, 3co6_C, 6ako_C, 7yzg_A, 7tdw_A, 3g73_A, 7yz7_A, 6el8_A, 7tdx_A, 3l2c_A, 2a07_J, 6nce_A, 2uzk_A, 7vou_C, 2c6y_A, 3qrf_G, 2o4a_A
Binding Motifs: UP00039A_1 hraarRTAAACAAwsmc
Foxj3_DBD_1 ACGGACACAAT
Foxj3_DBD_2 GTAAACArTmAACA
Foxj3_DBD_3 rTAAACAa
Foxj3_DBD_4 rTAAACAwAAACA
UP00039A_2 awbrcCmwAACAwwksw
Binding Sites: GTAAACAA
AATAAACA
AGTAAACA
ATAAACAA
ATAAACAC
ATAAACAT
ATGTTTAC
ATTGTTTA
CATAAACA
CGTAAACA
CTGTTTAC
GATAAACA
GGTAAACA
GTAAACAC
GTAAATAA
GTTGTTTA
TAAACAAA
TAAACATA
TATAAACA
TGTAAACA
Publications: Jolma A, Yan J, Whitington T, Toivonen J, Nitta KR, Rastas P, Morgunova E, Enge M, Taipale M, Wei G, Palin K, Vaquerizas JM, Vincentelli R, Luscombe NM, Hughes TR, Lemaire P, Ukkonen E, Kivioja T, Taipale J. DNA-Binding Specificities of Human Transcription Factors. Cell. 2013 Jan 17;152(1-2):327-39. [Pubmed]

Badis G, Berger M.F, Philippakis A.A, Talukder S, Gehrke A.R, Jaeger S.A, Chan E.T, Metzler G, Vedenko A, Chen X, Kuznetsov H, Wang C.F, Coburn D, Newburger D.E, Morris Q, Hughes T.R, Bulyk M.L. Diversity and complexity in DNA recognition by transcription factors. Science (New York, N.Y.) 324:1720-3 (2009). [Pubmed]
Related annotations: PaperBLAST

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These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.