Transcription Factor

Accessions: UP00361A (UniPROBE 20160601)
Names: HLH-15
Organisms: Caenorhabditis elegans
Libraries: UniPROBE 20160601 1
1 Hume MA, Barrera LA, Gisselbrecht SS, Bulyk ML. UniPROBE, update 2015: new tools and content for the online database of protein-binding microarray data on protein-DNA interactions. Nucleic Acids Res : (2015). [Pubmed]
Uniprot: Q18590
Description: Helix Loop Helix Protein 15 : none available
Length: 88
Pfam Domains: 33-83 Helix-loop-helix DNA-binding domain
Sequence:
(in bold interface residues)
1 LMEDGGLDTTSEEYRKLSKAERRKRRRATPKYRNLHATRERIRVESFNMAFSQLRALLPT 60
61 LPVEKKLSKIEILRFSIAYISFLDNLLQ
Interface Residues: 36, 37, 39, 40, 41, 43, 44
3D-footprint Homologues: 4h10_A, 8osl_P, 2ypa_A, 7z5k_B, 2ypa_B, 6od3_F, 2ql2_D
Binding Motifs: UP00361A_1 agwaaaawrwhdwr
UP00361A_2 rrmsCAsCTGbGccmt
Binding Sites: AACACCTG
AACAGCTG
ACACCTGC
ACACCTGT
ACAGCTGC
ACAGCTGG
ACAGCTGT
ACCACCTG
ACCAGCTG
AGCAGCTG
AGCAGGTG
CACAGCTG
CACAGGTG
CACCTGCG
CAGCTGCG
CAGGTGCG
CCACCTGC
GCAGCTGC
CAGCTGGG
CCAGCTGG
Publications: Grove C.A, De Masi F, Barrasa M.I, Newburger D.E, Alkema M.J, Bulyk M.L, Walhout A.J. A multiparameter network reveals extensive divergence between C. elegans bHLH transcription factors. Cell 138:314-27 (2009). [Pubmed]
Related annotations: PaperBLAST

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