DNA Binding Site
| Accessions: | ACAGCTGT (UniPROBE 20160601), MA1472.3.10 (JASPAR 2024), MA1472.3.9 (JASPAR 2024), MA1619.2.19 (JASPAR 2024), MA1619.2.20 (JASPAR 2024), MA1620.2.11 (JASPAR 2024), MA1620.2.12 (JASPAR 2024), MA1620.2.15 (JASPAR 2024), MA1620.2.16 (JASPAR 2024), MA1620.2.20 (JASPAR 2024), MA1620.2.8 (JASPAR 2024), MA1620.2.9 (JASPAR 2024) |
| Organisms: | Mus musculus, Caenorhabditis elegans, Homo sapiens |
| Libraries: | UniPROBE 20160601 1, JASPAR 2024 2 1 Hume MA, Barrera LA, Gisselbrecht SS, Bulyk ML. UniPROBE, update 2015: new tools and content for the online database of protein-binding microarray data on protein-DNA interactions. Nucleic Acids Res : (2015). [Pubmed] 2 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed] |
| Length: | 8 |
| Sequence: | ACAGCTGT |
| Type: | Heterodimer |
| Binding TFs: | UP00036A (Helix-loop-helix DNA-binding domain, Myogenic Basic domain) UP00099A (Helix-loop-helix DNA-binding domain) UP00357A (Helix-loop-helix DNA-binding domain) UP00358A (Helix-loop-helix DNA-binding domain) UP00359A (Helix-loop-helix DNA-binding domain, Neuronal helix-loop-helix transcription factor ) UP00361A (Helix-loop-helix DNA-binding domain) UP00363A (Helix-loop-helix DNA-binding domain) UP00378A (Helix-loop-helix DNA-binding domain) UP00379A (Helix-loop-helix DNA-binding domain) UP00381A (Helix-loop-helix DNA-binding domain) UP00384A (Helix-loop-helix DNA-binding domain) UP00387A (Helix-loop-helix DNA-binding domain) UP00548A (Helix-loop-helix DNA-binding domain) Q9QYC3 (Helix-loop-helix DNA-binding domain) UP00548C (Helix-loop-helix DNA-binding domain) UP00548D (Helix-loop-helix DNA-binding domain) Q9QX98 (Helix-loop-helix DNA-binding domain) Q9QX98 Q9QYC3 |
| Binding Motifs: | UP00036A_1 rrrgrACAGbTGtyyg UP00099A_1 ytyarCAGCTGCtvytk UP00357A_1 whyrATCAGCTGatsk UP00358A_1 wAyyAwATwTrgmm UP00359A_1 wkdraaaaraastm UP00361A_1 agwaaaawrwhdwr UP00363A_1 cwhaaaawawwwAa UP00378A_1 ctwwramwwwmmaw UP00381A_1 akwraTwagwaswm UP00387A_1 ksrACAGCTGTyrwrr UP00036A_2 vsmrmCAgmCgcrcc UP00099A_2 bymwcCCcryccyrty UP00358A_2 / UP00384A_3 yvsamCACCTGTTmcrg UP00359A_2 / UP00384A_2 mskaACAkCTGTyyaa UP00361A_2 / UP00384A_5 rrmsCAsCTGbGccmt UP00363A_2 / UP00384A_4 ykaaCAbCTGTCvmda UP00378A_2 / UP00384A_6 kktrmCAksTGkymmh UP00379A_2 / UP00384A_7 mrtrmCACCTGCtaayy UP00381A_2 / UP00384A_10 hmgamCAgcTGkymtc UP00548A_1 sGgamrGrCACGTGtCsyhCysy UP00548C_1 rywgggRACAGCTGtyyksracm UP00548D_1 mrkrkrkRACAGcTGTymgrkmm MA1472.3 ACAGCTGT MA1619.2 aCAGCTGt MA1620.2 aCACCTGt |
| Publications: | Badis G, Berger M.F, Philippakis A.A, Talukder S, Gehrke A.R, Jaeger S.A, Chan E.T, Metzler G, Vedenko A, Chen X, Kuznetsov H, Wang C.F, Coburn D, Newburger D.E, Morris Q, Hughes T.R, Bulyk M.L. Diversity and complexity in DNA recognition by transcription factors. Science (New York, N.Y.) 324:1720-3 (2009). [Pubmed] Lo HG, Jin RU, Sibbel G, Liu D, Karki A, Joens MS, Madison BB, Zhang B, Blanc V, Fitzpatrick JA, Davidson NO, Konieczny SF, Mills JC. A single transcription factor is sufficient to induce and maintain secretory cell architecture. Genes Dev 31:154-171 (2017). [Pubmed] Meredith DM, Borromeo MD, Deering TG, Casey BH, Savage TK, Mayer PR, Hoang C, Tung KC, Kumar M, Shen C, Swift GH, Macdonald RJ, Johnson JE. Program specificity for Ptf1a in pancreas versus neural tube development correlates with distinct collaborating cofactors and chromatin accessibility. Mol Cell Biol 33:3166-79 (2013). [Pubmed] |
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