DNA Binding Site

Accessions: TCAATTAA (UniPROBE 20160601), MA2158.1.4 (JASPAR 2024)
Organisms: Mus musculus, Saccharomyces cerevisiae, Homo sapiens, Caenorhabditis elegans
Libraries: UniPROBE 20160601 1, JASPAR 2024 2
1 Hume MA, Barrera LA, Gisselbrecht SS, Bulyk ML. UniPROBE, update 2015: new tools and content for the online database of protein-binding microarray data on protein-DNA interactions. Nucleic Acids Res : (2015). [Pubmed]
2 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed]
Length: 8
Sequence: TCAATTAA
Type: Heterodimer
Binding TFs: UP00224A (Homeobox domain, 'Paired box' domain)
UP00104A (Homeobox domain)
UP00141A (Homeobox domain)
UP00155A (Homeobox domain)
UP00170A (Homeobox domain, Homeobox KN domain)
UP00178A (Homeobox domain)
UP00244A (Homeobox domain)
UP00255A (Homeobox domain)
UP00274A (Homeobox domain)
UP00157A (Homeobox domain)
UP00598A (Homeobox domain)
UP00598B (Homeobox domain)
P20271
Binding Motifs: UP00255A_1 twrttaATTAwtaawwr
UP00104A_1 msvAGCAATTAAwgvwt
UP00141A_1 csaryTAATTAryratt
UP00155A_1 acaAgCAATTAAwgvrT
UP00157A_1 asaAgCAATTAAwrrat
UP00170A_1 mhmaAyymMTTAakwy
UP00178A_1 cgsryyAATTrrkways
UP00224A_1 TrayTAATTArtkvac
UP00244A_1 kwatyAATTAATaayww
UP00274A_1 ttsmmaYTAATTARwwwmks
UP00598A_2 makkcmaACYAATTAdswsdky
UP00598B_2 gkcmscryTAATTArkvhkssb
MA2158.1 tTAATTAa
Publications: Berger M.F, Badis G, Gehrke A.R, Talukder S, Philippakis A.A, Peña-Castillo L, Alleyne T.M, Mnaimneh S, Botvinnik O.B, Chan E.T, Khalid F, Zhang W, Newburger D, Jaeger S.A, Morris Q.D, Bulyk M.L, Hughes T.R. Variation in homeodomain DNA binding revealed by high-resolution analysis of sequence preferences. Cell 133:1266-76 (2008). [Pubmed]

Kagoshima H, Kohara Y. Co-expression of the transcription factors CEH-14 and TTX-1 regulates AFD neuron-specific genes gcy-8 and gcy-18 in C. elegans 399:325-36 (Dev). [Pubmed]

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