DNA Binding Motif

Accessions: UP00255A_1 (UniPROBE 20160601)
Names: AI426026, Dbx1, developing brain homeobox 1, Homeobox protein DBX1, Mmox C
Organisms: Mus musculus
Libraries: UniPROBE 20160601 1
1 Hume MA, Barrera LA, Gisselbrecht SS, Bulyk ML. UniPROBE, update 2015: new tools and content for the online database of protein-binding microarray data on protein-DNA interactions. Nucleic Acids Res : (2015). [Pubmed]
Length: 17
Consensus: twrttaATTAwtaawwr
Weblogo:
PSSM: P0 A C G T
01 0.19 0.23 0.16 0.42 t
02 0.61 0.07 0.05 0.27 w
03 0.46 0.06 0.31 0.18 r
04 0.23 0.13 0.10 0.55 t
05 0.24 0.23 0.07 0.46 t
06 0.62 0.14 0.08 0.16 a
07 0.74 0.03 0.05 0.18 A
08 0.11 0.10 0.07 0.72 T
09 0.13 0.11 0.04 0.72 T
10 0.73 0.03 0.09 0.15 A
11 0.54 0.10 0.05 0.31 w
12 0.20 0.15 0.10 0.56 t
13 0.59 0.07 0.17 0.17 a
14 0.50 0.16 0.22 0.12 a
15 0.28 0.11 0.14 0.47 w
16 0.30 0.19 0.19 0.33 w
17 0.40 0.14 0.29 0.17 r
Binding TFs: UP00255A (Homeobox domain)
Binding Sites: TAATAAAA
AATAATAA
AATAATTA
AATATATT
AATTAATA
AATTAATG
ACTAATTA
ATAAATTA
ATAATTAA
ATAATTAC
ATAATTAT
ATCAATTA
ATTAATGA
ATTAATTA
ATTAATTG
CTAATTAG
TAATAATA
TAATTATA
TCAATTAA
TCATTAAA
Publications: Berger M.F, Badis G, Gehrke A.R, Talukder S, Philippakis A.A, Peña-Castillo L, Alleyne T.M, Mnaimneh S, Botvinnik O.B, Chan E.T, Khalid F, Zhang W, Newburger D, Jaeger S.A, Morris Q.D, Bulyk M.L, Hughes T.R. Variation in homeodomain DNA binding revealed by high-resolution analysis of sequence preferences. Cell 133:1266-76 (2008). [Pubmed]

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