Transcription Factor

Accessions: UP00255A (UniPROBE 20160601)
Names: AI426026, Dbx1, developing brain homeobox 1, Homeobox protein DBX1, Mmox C
Organisms: Mus musculus
Libraries: UniPROBE 20160601 1
1 Hume MA, Barrera LA, Gisselbrecht SS, Bulyk ML. UniPROBE, update 2015: new tools and content for the online database of protein-binding microarray data on protein-DNA interactions. Nucleic Acids Res : (2015). [Pubmed]
Uniprot: P52950
Description: developing brain homeobox 1
Length: 93
Pfam Domains: 19-73 Homeobox domain
Sequence:
(in bold interface residues)
1 GTFSWPLAARGKPRRGMLRRAVFSDVQRKALEKTFQKQKYISKPDRKKLASKLGLKDSQV 60
61 KIWFQNRRMKWRNSKERELLSSGGCREQTLPTK
Interface Residues: 15, 17, 18, 19, 20, 38, 58, 59, 61, 62, 65, 66, 69, 70, 73, 85, 88
3D-footprint Homologues: 1zq3_P, 5zfz_A, 3d1n_M, 1nk2_P, 2ld5_A, 2d5v_B, 1jgg_B, 5hod_A, 1puf_A, 6a8r_A, 3a01_E, 2h1k_B, 7psx_B, 1au7_A, 5jlw_D, 3lnq_A, 2lkx_A, 1fjl_B, 6es3_K, 4xrs_G, 3cmy_A, 2hdd_A, 7q3o_C, 1b72_A, 3rkq_B, 2r5y_A, 1ig7_A, 6m3d_C, 5flv_I, 2hos_A, 5zjt_E, 4cyc_A, 7n8n_A, 1e3o_C, 1le8_A, 7xrc_C, 2xsd_C, 3l1p_A, 8g87_X, 4qtr_D, 1puf_B, 1o4x_A, 1du0_A
Binding Motifs: UP00255A_1 twrttaATTAwtaawwr
Binding Sites: TAATAAAA
AATAATAA
AATAATTA
AATATATT
AATTAATA
AATTAATG
ACTAATTA
ATAAATTA
ATAATTAA
ATAATTAC
ATAATTAT
ATCAATTA
ATTAATGA
ATTAATTA
ATTAATTG
CTAATTAG
TAATAATA
TAATTATA
TCAATTAA
TCATTAAA
Publications: Berger M.F, Badis G, Gehrke A.R, Talukder S, Philippakis A.A, Peña-Castillo L, Alleyne T.M, Mnaimneh S, Botvinnik O.B, Chan E.T, Khalid F, Zhang W, Newburger D, Jaeger S.A, Morris Q.D, Bulyk M.L, Hughes T.R. Variation in homeodomain DNA binding revealed by high-resolution analysis of sequence preferences. Cell 133:1266-76 (2008). [Pubmed]
Related annotations: PaperBLAST

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These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.