DNA Binding Site

Accessions: ACATATGG (UniPROBE 20160601), MA0668.3.18 (JASPAR 2024), MA2170.1.5 (JASPAR 2024)
Organisms: Caenorhabditis elegans, Mus musculus
Libraries: UniPROBE 20160601 1, JASPAR 2024 2
1 Hume MA, Barrera LA, Gisselbrecht SS, Bulyk ML. UniPROBE, update 2015: new tools and content for the online database of protein-binding microarray data on protein-DNA interactions. Nucleic Acids Res : (2015). [Pubmed]
2 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed]
Length: 8
Sequence: ACATATGG
Type: Heterodimer
Binding TFs: UP00359A (Helix-loop-helix DNA-binding domain, Neuronal helix-loop-helix transcription factor )
UP00371A (Helix-loop-helix DNA-binding domain)
UP00378A (Helix-loop-helix DNA-binding domain)
UP00381A (Helix-loop-helix DNA-binding domain)
UP00384A (Helix-loop-helix DNA-binding domain)
Q62414 (Helix-loop-helix DNA-binding domain, Neuronal helix-loop-helix transcription factor )
Q10574
Q62414
Binding Motifs: UP00359A_1 wkdraaaaraastm
UP00371A_1 wtaAAwaAAacymw
UP00378A_1 ctwwramwwwmmaw
UP00381A_1 akwraTwagwaswm
UP00359A_2 / UP00384A_2 mskaACAkCTGTyyaa
UP00371A_2 / UP00384A_9 aymaACATmTGGtwkm
UP00378A_2 / UP00384A_6 kktrmCAksTGkymmh
UP00381A_2 / UP00384A_10 hmgamCAgcTGkymtc
MA0668.3 aCAGATGG
MA2170.1 ACAGrTGk
Publications: Grove C.A, De Masi F, Barrasa M.I, Newburger D.E, Alkema M.J, Bulyk M.L, Walhout A.J. A multiparameter network reveals extensive divergence between C. elegans bHLH transcription factors. Cell 138:314-27 (2009). [Pubmed]

Fong AP, Yao Z, Zhong JW, Cao Y, Ruzzo WL, Gentleman RC, Tapscott SJ. Genetic and epigenetic determinants of neurogenesis and myogenesis. Dev Cell 22:721-35 (2012). [Pubmed]

Portman DS, Emmons SW. The basic helix-loop-helix transcription factors LIN-32 and HLH-2 function together in multiple steps of a C. elegans neuronal sublineage 127:5415-26 (Development.). [Pubmed]

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These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.