DNA Binding Motif

Accessions: UP00378A_1 (UniPROBE 20160601)
Names: HLH-19
Organisms: Caenorhabditis elegans
Libraries: UniPROBE 20160601 1
1 Hume MA, Barrera LA, Gisselbrecht SS, Bulyk ML. UniPROBE, update 2015: new tools and content for the online database of protein-binding microarray data on protein-DNA interactions. Nucleic Acids Res : (2015). [Pubmed]
Length: 14
Consensus: ctwwramwwwmmaw
Weblogo:
PSSM: P0 A C G T
01 0.20 0.34 0.22 0.24 c
02 0.16 0.23 0.22 0.38 t
03 0.27 0.13 0.21 0.39 w
04 0.47 0.09 0.18 0.27 w
05 0.44 0.09 0.30 0.17 r
06 0.51 0.17 0.13 0.18 a
07 0.40 0.28 0.16 0.16 m
08 0.50 0.06 0.15 0.29 w
09 0.54 0.09 0.06 0.31 w
10 0.38 0.15 0.15 0.32 w
11 0.40 0.32 0.06 0.21 m
12 0.34 0.38 0.10 0.18 m
13 0.62 0.12 0.08 0.17 a
14 0.35 0.23 0.06 0.36 w
Binding TFs: UP00378A (Helix-loop-helix DNA-binding domain)
Binding Sites: AAAATTTT
AACACCTG
AACAGCTG
AACAGGTG
AACATATG
ACACCTGT
ACAGCTGC
ACAGCTGG
ACAGCTGT
ACCACCTG
ACCAGCTG
CAGCTGTC
AACATCTG
ACAGGTGG
ACATATGG
ACATCTGG
CAGCTGGG
CCAGATGG
CCAGCTGG
CCATATGG
Publications: Grove C.A, De Masi F, Barrasa M.I, Newburger D.E, Alkema M.J, Bulyk M.L, Walhout A.J. A multiparameter network reveals extensive divergence between C. elegans bHLH transcription factors. Cell 138:314-27 (2009). [Pubmed]

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