Transcription Factor
| Accessions: | Q62414 (JASPAR 2024) |
| Names: | NDF2_MOUSE, NDRF, NeuroD-related factor, NeuroD2, Neurogenic differentiation factor 2 |
| Organisms: | Mus musculus |
| Libraries: | JASPAR 2024 1 1 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed] |
| Uniprot: | Q62414 |
| Length: | 383 |
| Pfam Domains: | 123-174 Helix-loop-helix DNA-binding domain 181-311 Neuronal helix-loop-helix transcription factor |
| Sequence: (in bold interface residues) | 1 MLTRLFSEPGLLSDVPKFASWGDGDDDEPRSDKGDAPPQPPPAPGSGAPGPARAAKPVSL 60 61 RGGEEIPEPTLAEVKEEGELGGEEEEEEEEEEGLDEAEGERPKKRGPKKRKMTKARLERS 120 121 KLRRQKANARERNRMHDLNAALDNLRKVVPCYSKTQKLSKIETLRLAKNYIWALSEILRS 180 181 GKRPDLVSYVQTLCKGLSQPTTNLVAGCLQLNSRNFLTEQGADGAGRFHGSGGPFAMHPY 240 241 PYPCSRLAGAQCQAAGGLGGGAAHALRTHGYCAAYETLYAAAGGGGASPDYNSSEYEGPL 300 301 SPPLCLNGNFSLKQDSSPDHEKSYHYSMHYSALPGSRPTGHGLVFGSSAVRGGVHSENLL 360 361 SYDMHLHHDRGPMYEELNAFFHN |
| Interface Residues: | 124, 127, 128, 130, 131, 132, 134, 135 |
| 3D-footprint Homologues: | 2ypa_A, 7z5k_B, 6od3_F, 2ypa_B, 2ql2_A, 2ql2_D |
| Binding Motifs: | MA0668.2 rrgraCAGATGGysv MA1993.1 rvCAGCTGby MA0668.3 aCAGATGG MA1993.2 CAGCTG |
| Binding Sites: | MA1993.2.1 / MA1993.2.10 / MA1993.2.11 / MA1993.2.12 / MA1993.2.13 / MA1993.2.14 / MA1993.2.15 / MA1993.2.16 / MA1993.2.17 / MA1993.2.18 / MA1993.2.19 / MA1993.2.2 / MA1993.2.20 / MA1993.2.3 / MA1993.2.4 / MA1993.2.5 / MA1993.2.6 / MA1993.2.7 / MA1993.2.8 / MA1993.2.9 MA0668.3.10 / MA0668.3.14 / MA0668.3.15 MA0668.3.2 / MA0668.3.5 / MA0668.3.7 / MA0668.3.8 MA0668.3.18 MA0668.3.11 / MA0668.3.13 / MA0668.3.17 / MA0668.3.20 / MA0668.3.3 / MA0668.3.4 / MA0668.3.6 / MA0668.3.9 MA1993.1.12 MA1993.1.11 MA1993.1.17 MA1993.1.18 MA1993.1.2 / MA1993.1.5 MA1993.1.1 / MA1993.1.6 MA0668.2.1 MA0668.2.10 MA0668.2.11 MA0668.2.12 MA0668.2.13 MA0668.2.14 MA0668.2.15 MA0668.2.16 MA0668.2.17 MA0668.2.18 MA0668.2.19 MA0668.2.2 / MA0668.2.4 MA0668.2.20 MA0668.2.3 / MA0668.2.6 MA0668.2.4 / MA0668.2.8 MA0668.2.12 / MA0668.2.5 MA0668.2.13 / MA0668.2.6 MA0668.2.19 / MA0668.2.7 MA0668.2.8 MA0668.2.9 MA1993.1.10 MA1993.1.13 MA1993.1.14 MA1993.1.15 MA1993.1.16 MA1993.1.19 MA1993.1.20 MA1993.1.3 MA1993.1.4 MA1993.1.7 MA1993.1.8 MA1993.1.9 MA0668.2.10 MA0668.2.11 MA0668.2.14 MA0668.2.15 MA0668.2.16 MA0668.2.17 MA0668.2.18 MA0668.2.2 MA0668.2.20 MA0668.2.3 MA0668.2.5 MA0668.2.7 MA0668.2.9 MA0668.3.1 MA0668.3.12 / MA0668.3.16 MA0668.3.19 |
| Publications: | Fong AP, Yao Z, Zhong JW, Cao Y, Ruzzo WL, Gentleman RC, Tapscott SJ. Genetic and epigenetic determinants of neurogenesis and myogenesis. Dev Cell 22:721-35 (2012). [Pubmed] |
| Related annotations: | PaperBLAST |
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