DNA Binding Site
| Accessions: | GGTGGGAA (UniPROBE 20160601), MA0471.3.15 (JASPAR 2024) |
| Organisms: | Homo sapiens |
| Libraries: | UniPROBE 20160601 1, JASPAR 2024 2 1 Hume MA, Barrera LA, Gisselbrecht SS, Bulyk ML. UniPROBE, update 2015: new tools and content for the online database of protein-binding microarray data on protein-DNA interactions. Nucleic Acids Res : (2015). [Pubmed] 2 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed] |
| Length: | 8 |
| Sequence: | GGTGGGAA |
| Type: | Heterodimer |
| Binding TFs: | O75461 (E2F/DP family winged-helix DNA-binding domain) UP00480A (Ankyrin repeat, Ankyrin repeats (3 copies), Ankyrin repeat, Ankyrin repeats (many copies), Ankyrin repeats (many copies)) UP00481A (Ankyrin repeat, Ankyrin repeats (3 copies), Ankyrin repeat, Ankyrin repeats (many copies), Ankyrin repeats (many copies)) UP00482A (Ankyrin repeat, Ankyrin repeats (3 copies), Ankyrin repeat, Ankyrin repeats (many copies), Ankyrin repeats (many copies)) UP00483A (Ankyrin repeat, Ankyrin repeats (3 copies), Ankyrin repeat, Ankyrin repeats (many copies), Ankyrin repeats (many copies)) UP00484A (IPT/TIG domain, Beta-trefoil DNA-binding domain, LAG1, DNA binding) UP00485A (MamL-1 domain) O75461 |
| Binding Motifs: | UP00480A_4 / UP00484A_4 wtmccrTGGGAAcwwk UP00480A_5 / UP00484A_5 / UP00485A_1 ksmscgTGGGAayswst UP00480A_6 / UP00484A_6 / UP00485A_2 yckwwhscrTGGGAAmywkwkrg UP00480A_7 / UP00484A_7 / UP00485A_3 yykrcaycgTGGGAACcvcdwtg UP00481A_1 / UP00484A_8 / UP00485A_4 tmkrmaycvTGGGAAccmbdwkg UP00481A_2 / UP00484A_9 / UP00485A_5 cwckwwwsCrTGGGAAmhwktkd UP00482A_1 / UP00484A_10 / UP00485A_6 yyckwwhsCgTGGGAAmywytkd UP00483A_1 / UP00484A_11 / UP00485A_7 tykrmwhcvTGGGAAccmswadg UP00484A_2 gvmsCGTGGGAAmywck UP00484A_3 yswrcmgCGTGGGAAccwstsk MA0471.3 GGCGGGAA |
| Publications: | Del Bianco C, Vedenko A, Choi SH, Berger MF, Shokri L, Bulyk ML, Blacklow SC. Notch and MAML-1 complexation do not detectably alter the DNA binding specificity of the transcription factor CSL. PLoS One : (2010). [Pubmed] Xu X., Bieda M., Jin V. X., Rabinovich A., Oberley M. J., Green R., Farnham P. J. A comprehensive ChIP-chip analysis of E2F1, E2F4, and E2F6 in normal and tumor cells reveals interchangeable roles of E2F family members.. Genome Res. 17:1550-1561 (2007). [Pubmed] |
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