DNA Binding Motif

						

			
Accessions: UP00481A_2 (UniPROBE 20160601), UP00484A_9 (UniPROBE 20160601), UP00485A_5 (UniPROBE 20160601)

			
Names: AGS2, HJCYS, hN2, MAML1-CSL-GST-NOTCH2_Fig5, notch 2, CBF1, IGKJRB, IGKJRB1, KBF2, MGC61669, RBP-J, RBPJ, RBPJK, RBPSUH, recombination signal binding protein for immunoglobulin kappa J region, SUH, FLJ53540, KIAA0200, Mam-1, Mam1, MAML 1, MAML-1, mastermind-like 1 (Drosophila)
Organisms: Homo sapiens
Libraries: UniPROBE 20160601 1
1 Hume MA, Barrera LA, Gisselbrecht SS, Bulyk ML. UniPROBE, update 2015: new tools and content for the online database of protein-binding microarray data on protein-DNA interactions. Nucleic Acids Res : (2015). [Pubmed]
Length: 23
Consensus: cwckwwwsCrTGGGAAmhwktkd
Weblogo: 
PSSM: P0      A      C      G      T
01   0.17   0.45   0.15   0.23      c
02   0.27   0.24   0.18   0.31      w
03   0.22   0.37   0.18   0.23      c
04   0.13   0.13   0.30   0.45      k
05   0.26   0.21   0.14   0.39      w
06   0.35   0.13   0.16   0.36      w
07   0.34   0.24   0.15   0.26      w
08   0.04   0.54   0.33   0.09      s
09   0.03   0.75   0.12   0.10      C
10   0.25   0.16   0.55   0.04      r
11   0.02   0.01      0   0.96      T
12   0.01      0   0.98   0.01      G
13   0.10   0.01   0.87   0.02      G
14   0.03      0   0.96      0      G
15   0.97      0   0.01   0.01      A
16   0.91   0.02   0.05   0.01      A
17   0.42   0.36   0.09   0.13      m
18   0.26   0.25   0.08   0.41      h
19   0.50   0.05   0.09   0.35      w
20   0.09   0.24   0.31   0.36      k
21   0.18   0.20   0.22   0.40      t
22   0.12   0.17   0.27   0.44      k
23   0.35   0.09   0.25   0.31      d
Type: Heterodimer
Binding TFs: UP00481A (Ankyrin repeat, Ankyrin repeats (3 copies), Ankyrin repeat, Ankyrin repeats (many copies), Ankyrin repeats (many copies))
UP00484A (IPT/TIG domain, Beta-trefoil DNA-binding domain, LAG1, DNA binding)
UP00485A (MamL-1 domain)
Binding Sites: GCGTGGGA
AGTTCCCA
ATGGGAAA
ATGGGAAC
ATTCCCAC
CATGGGAA
CCGTGGGA
CCTGGGAA
CGTGAGAA
CGTGGGAA
CTGGGAAC
CTTTCCCA
GGTGGGAA
GGTTCCCA
GTGGGAAA
GTGGGAAC
GTTTCCCA
TATGGGAA
TGGGAAAA
TGTGGGAA
			
Publications: Del Bianco C, Vedenko A, Choi SH, Berger MF, Shokri L, Bulyk ML, Blacklow SC. Notch and MAML-1 complexation do not detectably alter the DNA binding specificity of the transcription factor CSL. PLoS One : (2010). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.