DNA Binding Site
| Accessions: | ACAGGTGG (UniPROBE 20160601), MA1109.2.18 (JASPAR 2024), MA1109.2.7 (JASPAR 2024), MA1109.2.8 (JASPAR 2024), MA2170.1.14 (JASPAR 2024) |
| Organisms: | Caenorhabditis elegans, Homo sapiens |
| Libraries: | UniPROBE 20160601 1, JASPAR 2024 2 1 Hume MA, Barrera LA, Gisselbrecht SS, Bulyk ML. UniPROBE, update 2015: new tools and content for the online database of protein-binding microarray data on protein-DNA interactions. Nucleic Acids Res : (2015). [Pubmed] 2 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed] |
| Length: | 8 |
| Sequence: | ACAGGTGG |
| Type: | Heterodimer |
| Binding TFs: | UP00358A (Helix-loop-helix DNA-binding domain) UP00378A (Helix-loop-helix DNA-binding domain) UP00379A (Helix-loop-helix DNA-binding domain) UP00381A (Helix-loop-helix DNA-binding domain) UP00384A (Helix-loop-helix DNA-binding domain) Q13562 (Helix-loop-helix DNA-binding domain, Neuronal helix-loop-helix transcription factor ) UP00621A (Zinc finger, C2H2 type, Zinc-finger of C2H2 type, Zinc-finger double domain, C2H2-type zinc finger, C2H2-type zinc finger) UP00621B (Zinc finger, C2H2 type, Zinc-finger of C2H2 type, Zinc-finger double domain, C2H2-type zinc finger, C2H2-type zinc finger) UP00621C (Zinc finger, C2H2 type, Zinc-finger of C2H2 type, Zinc-finger double domain, C2H2-type zinc finger, C2H2-type zinc finger) Q10574 Q13562 |
| Binding Motifs: | UP00358A_1 wAyyAwATwTrgmm UP00378A_1 ctwwramwwwmmaw UP00381A_1 akwraTwagwaswm UP00358A_2 / UP00384A_3 yvsamCACCTGTTmcrg UP00378A_2 / UP00384A_6 kktrmCAksTGkymmh UP00379A_2 / UP00384A_7 mrtrmCACCTGCtaayy UP00381A_2 / UP00384A_10 hmgamCAgcTGkymtc UP00621A_1 wmkaratrCACCTGyTakwhmk UP00621B_1 wwwmrakrCACCTGyTakwhaw UP00621C_1 tadarAwrCACCTGyTakwyad MA1109.2 aCAGATGG MA2170.1 ACAGrTGk |
| Publications: | Grove C.A, De Masi F, Barrasa M.I, Newburger D.E, Alkema M.J, Bulyk M.L, Walhout A.J. A multiparameter network reveals extensive divergence between C. elegans bHLH transcription factors. Cell 138:314-27 (2009). [Pubmed] Sharma A, Moore M, Marcora E, Lee JE, Qiu Y, Samaras S, Stein R. The NeuroD1/BETA2 sequences essential for insulin gene transcription colocalize with those necessary for neurogenesis and p300/CREB binding protein binding. Mol Cell Biol 19:704-13 (1999). [Pubmed] Portman DS, Emmons SW. The basic helix-loop-helix transcription factors LIN-32 and HLH-2 function together in multiple steps of a C. elegans neuronal sublineage 127:5415-26 (Development.). [Pubmed] |
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