Transcription Factor
| Accessions: | UP00358A (UniPROBE 20160601) |
| Names: | HLH-10 |
| Organisms: | Caenorhabditis elegans |
| Libraries: | UniPROBE 20160601 1 1 Hume MA, Barrera LA, Gisselbrecht SS, Bulyk ML. UniPROBE, update 2015: new tools and content for the online database of protein-binding microarray data on protein-DNA interactions. Nucleic Acids Res : (2015). [Pubmed] |
| Uniprot: | Q23579 |
| Description: | Helix Loop Helix Protein 10: none available |
| Length: | 169 |
| Pfam Domains: | 89-139 Helix-loop-helix DNA-binding domain |
| Sequence: (in bold interface residues) | 1 QVMESCGMFLQQNLFAWFLQSMLEASASQPQLTQDEPPENDTKENDLVKQNKSEVNDENE 60 61 STPSPTQNSRRRTSTGKIDRRMVGKMCTRRYEANARERNRVQQLSKMFDQLRVCLPIEDD 120 121 AKISKLATLKVASSYIGYLGAILQENSNDEEEFKKQLQVELECAKTLRK |
| Interface Residues: | 68, 90, 93, 94, 96, 97, 100, 101 |
| 3D-footprint Homologues: | 7obn_A, 2ypa_A, 5eyo_A, 5i50_B, 2ql2_D, 5gnj_I |
| Binding Motifs: | UP00358A_1 wAyyAwATwTrgmm UP00358A_2 yvsamCACCTGTTmcrg |
| Binding Sites: | AACACCTG AACAGCTG AACAGGTG ACACCTGC ACACCTGG ACACCTGT ACAGCTGG ACAGCTGT ACAGGTGC ACCACCTG AGCAGGTG CACACCTG CACAGGTG CACCTGTC CCACCTGC CCAGGTGC ACAGGTGG CACCTGGC CAGGTGGC CCAGCTGG |
| Publications: | Grove C.A, De Masi F, Barrasa M.I, Newburger D.E, Alkema M.J, Bulyk M.L, Walhout A.J. A multiparameter network reveals extensive divergence between C. elegans bHLH transcription factors. Cell 138:314-27 (2009). [Pubmed] |
| Related annotations: | PaperBLAST |
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