DNA Binding Motif

						

			
Accessions: UP00621A_1 (UniPROBE 20160601)

			
Names: MGC10182, Neural crest transcription factor Slug, Protein snail homolog 2, SLUGH, SLUGH1, SNAI2_REF_R1, WS2D, zinc finger protein SNAI2
Organisms: Homo sapiens
Libraries: UniPROBE 20160601 1
1 Hume MA, Barrera LA, Gisselbrecht SS, Bulyk ML. UniPROBE, update 2015: new tools and content for the online database of protein-binding microarray data on protein-DNA interactions. Nucleic Acids Res : (2015). [Pubmed]
Length: 22
Consensus: wmkaratrCACCTGyTakwhmk
Weblogo: 
PSSM: P0      A      C      G      T
01   0.26   0.22   0.17   0.36      w
02   0.34   0.26   0.17   0.24      m
03   0.22   0.15   0.29   0.34      k
04   0.42   0.23   0.18   0.18      a
05   0.30   0.10   0.39   0.22      r
06   0.60   0.21   0.09   0.10      a
07   0.22   0.14   0.23   0.42      t
08   0.34   0.12   0.54   0.01      r
09   0.01   0.99      0   0.01      C
10   0.99      0      0      0      A
11      0   0.99      0      0      C
12      0   0.98      0   0.01      C
13      0      0      0   0.99      T
14      0      0   0.99   0.01      G
15   0.03   0.58      0   0.39      y
16   0.05   0.07   0.03   0.84      T
17   0.52   0.14   0.17   0.17      a
18   0.21   0.15   0.32   0.32      k
19   0.48   0.15   0.10   0.27      w
20   0.27   0.37   0.11   0.26      h
21   0.36   0.26   0.15   0.22      m
22   0.20   0.18   0.29   0.32      k
Binding TFs: UP00621A (Zinc finger, C2H2 type, Zinc-finger of C2H2 type, Zinc-finger double domain, C2H2-type zinc finger, C2H2-type zinc finger)
Binding Sites: AACAGGTG
ACACCTGC
ACACCTGT
ACAGGTGA
ACAGGTGC
AGCAGGTG
CACAGGTG
CACCTGCA
CACCTGCC
CACCTGCG
CACCTGTC
CAGGTGCA
CAGGTGCG
CCACCTGC
GCACCTGC
ACAGGTGG
CACCTGTA
CAGGTGGA
CAGGTGTA
CAGGTGTC
			
Publications: Barrera LA, Vedenko A, Kurland JV, Rogers JM, Gisselbrecht SS, Rossin EJ, Woodard J, Mariani L, Kock KH, Inukai S, Siggers T, Shokri L, Gordân R, Sahni N, Cotsapas C, Hao T, Yi S, Kellis M, Daly MJ, Vidal M, Hill DE, Bulyk ML. Survey of variation in human transcription factors reveals prevalent DNA binding changes. Science 351:1450-4 (2016). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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