Transcription Factor
| Accessions: | UP00046A (UniPROBE 20160601) |
| Names: | A1, AA408400, Alf2, AW209082, E12, E12/E47, Immunoglobulin enhancer-binding factor E12/E47, Me2, Pan1, Pan2, TCF-3, Tcf3, Tcfe2a, Transcription factor 3, Transcription factor A1, Transcription factor E2-alpha, transcription factor E2a, VDIR |
| Organisms: | Mus musculus |
| Libraries: | UniPROBE 20160601 1 1 Hume MA, Barrera LA, Gisselbrecht SS, Bulyk ML. UniPROBE, update 2015: new tools and content for the online database of protein-binding microarray data on protein-DNA interactions. Nucleic Acids Res : (2015). [Pubmed] |
| Uniprot: | P15806 |
| Description: | transcription factor E2a |
| Length: | 205 |
| Pfam Domains: | 101-153 Helix-loop-helix DNA-binding domain |
| Sequence: (in bold interface residues) | 1 HPEEGLTSGASLLHNHASLPSQPSSLPDLSQRPPDSYSGLGRAGTTAGASEIKREEKEDE 60 61 EIASVADAEEDKKDLKVPRTRTSSTDEVLSLEEKDLRDRERRMANNARERVRVRDINEAF 120 121 RELGRMCQLHLKSDKAQTKLLILQQAVQVILGLEQQVRERNLNPKAACLKRREEEKVSGV 180 181 VGDPQLPLSAAHPGLGEAHNPAGHL |
| Interface Residues: | 102, 105, 106, 108, 109, 110, 112, 113 |
| 3D-footprint Homologues: | 7z5k_B, 2ypa_A, 6od3_F, 2ql2_D, 2ypa_B, 2ql2_A |
| Binding Motifs: | UP00046A_1 atcmvCAGGTGcraamw UP00046A_2 arrgcCAGATGkyyssg |
| Binding Sites: | AACACCTG AACAGGTG ACACCTGG ACACCTGT ACAGGTGC ACCACCTG ACCAGGTG AGCACCTG AGCAGGTG CACACCTG CACAGGTG CACCTGCA CACCTGCC CACCTGCG CAGGTGCA CAGGTGCG CCACCTGC CCAGGTGC GCACCTGC CAGGTGTC |
| Publications: | Badis G, Berger M.F, Philippakis A.A, Talukder S, Gehrke A.R, Jaeger S.A, Chan E.T, Metzler G, Vedenko A, Chen X, Kuznetsov H, Wang C.F, Coburn D, Newburger D.E, Morris Q, Hughes T.R, Bulyk M.L. Diversity and complexity in DNA recognition by transcription factors. Science (New York, N.Y.) 324:1720-3 (2009). [Pubmed] |
| Related annotations: | PaperBLAST |
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These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.