DNA Binding Site

Accessions: ACAGGTGC (UniPROBE 20160601), MA2170.1.9 (JASPAR 2024)
Organisms: Mus musculus, Caenorhabditis elegans, Homo sapiens
Libraries: UniPROBE 20160601 1, JASPAR 2024 2
1 Hume MA, Barrera LA, Gisselbrecht SS, Bulyk ML. UniPROBE, update 2015: new tools and content for the online database of protein-binding microarray data on protein-DNA interactions. Nucleic Acids Res : (2015). [Pubmed]
2 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed]
Length: 8
Sequence: ACAGGTGC
Type: Heterodimer
Binding TFs: UP00099A (Helix-loop-helix DNA-binding domain)
UP00046A (Helix-loop-helix DNA-binding domain)
UP00358A (Helix-loop-helix DNA-binding domain)
UP00363A (Helix-loop-helix DNA-binding domain)
UP00369A (Helix-loop-helix DNA-binding domain)
UP00384A (Helix-loop-helix DNA-binding domain)
UP00548A (Helix-loop-helix DNA-binding domain)
UP00548D (Helix-loop-helix DNA-binding domain)
UP00621A (Zinc finger, C2H2 type, Zinc-finger of C2H2 type, Zinc-finger double domain, C2H2-type zinc finger, C2H2-type zinc finger)
UP00621B (Zinc finger, C2H2 type, Zinc-finger of C2H2 type, Zinc-finger double domain, C2H2-type zinc finger, C2H2-type zinc finger)
UP00621C (Zinc finger, C2H2 type, Zinc-finger of C2H2 type, Zinc-finger double domain, C2H2-type zinc finger, C2H2-type zinc finger)
Q10574
Binding Motifs: UP00046A_1 atcmvCAGGTGcraamw
UP00099A_1 ytyarCAGCTGCtvytk
UP00358A_1 wAyyAwATwTrgmm
UP00363A_1 cwhaaaawawwwAa
UP00369A_1 mawwaawaAaadgw
UP00046A_2 arrgcCAGATGkyyssg
UP00099A_2 bymwcCCcryccyrty
UP00358A_2 / UP00384A_3 yvsamCACCTGTTmcrg
UP00363A_2 / UP00384A_4 ykaaCAbCTGTCvmda
UP00369A_2 / UP00384A_8 arwwyCACCTGYthawy
UP00548A_1 sGgamrGrCACGTGtCsyhCysy
UP00548D_1 mrkrkrkRACAGcTGTymgrkmm
UP00621A_1 wmkaratrCACCTGyTakwhmk
UP00621B_1 wwwmrakrCACCTGyTakwhaw
UP00621C_1 tadarAwrCACCTGyTakwyad
MA2170.1 ACAGrTGk
Publications: Badis G, Berger M.F, Philippakis A.A, Talukder S, Gehrke A.R, Jaeger S.A, Chan E.T, Metzler G, Vedenko A, Chen X, Kuznetsov H, Wang C.F, Coburn D, Newburger D.E, Morris Q, Hughes T.R, Bulyk M.L. Diversity and complexity in DNA recognition by transcription factors. Science (New York, N.Y.) 324:1720-3 (2009). [Pubmed]

Portman DS, Emmons SW. The basic helix-loop-helix transcription factors LIN-32 and HLH-2 function together in multiple steps of a C. elegans neuronal sublineage 127:5415-26 (Development.). [Pubmed]

Disclaimer and license

These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.