Transcription Factor
| Accessions: | UP00125A (UniPROBE 20160601) |
| Names: | 9430085M16Rik, ALL1-responsive protein ARP1, Brx1, BRX1 homeoprotein, Brx1a, Brx1b, Munc30, Orthodenticle-like homeobox 2, Otlx2, paired-like homeodomain transcription factor 2, Paired-like homeodomain transcription factor Munc 30, Pituitary homeobox 2, Pitx2, Pitx2a, Pitx2b, Pitx2c, Ptx2, Rgs, Rieg, solurshin |
| Organisms: | Mus musculus |
| Libraries: | UniPROBE 20160601 1 1 Hume MA, Barrera LA, Gisselbrecht SS, Bulyk ML. UniPROBE, update 2015: new tools and content for the online database of protein-binding microarray data on protein-DNA interactions. Nucleic Acids Res : (2015). [Pubmed] |
| Uniprot: | P97474 |
| Description: | paired-like homeodomain transcription factor 2 |
| Length: | 93 |
| Pfam Domains: | 17-73 Homeobox domain |
| Sequence: (in bold interface residues) | 1 KNEDVGAEDPSKKKRQRRQRTHFTSQQLQELEATFQRNRYPDMSTREEIAVWTNLTEARV 60 61 RVWFKNRRAKWRKRERNQQAELCKNGFGPQFNG |
| Interface Residues: | 17, 18, 19, 20, 22, 58, 59, 61, 62, 65, 66, 69, 70, 73, 74 |
| 3D-footprint Homologues: | 1ig7_A, 2h1k_B, 1puf_A, 6a8r_A, 3cmy_A, 3d1n_M, 1fjl_B, 5zfz_A, 4j19_B, 3lnq_A, 2lkx_A, 1jgg_B, 1nk2_P, 1zq3_P, 6m3d_C, 2ld5_A, 1mnm_C, 5zjt_E, 3a01_E, 7psx_B, 5hod_A, 2hdd_A, 7q3o_C, 3rkq_B, 2r5y_A, 1puf_B, 6es3_K, 1au7_A, 4xrs_G, 2hos_A, 1b72_A, 5flv_I, 3l1p_A, 5jlw_D, 1e3o_C, 7xrc_C, 2xsd_C, 1le8_A, 1o4x_A, 8g87_X, 1le8_B, 1du0_A, 4qtr_D, 1k61_B, 4cyc_A |
| Binding Motifs: | UP00125A_1 kkwrrGGATTAAthrwy |
| Binding Sites: | ACTAATCC AGGATTAA AGGATTAG AGGATTAT AGGGATTA ATAATCCC ATTAATCC CCGGATTA CGGATTAA CTAATCCC CTTAATCC GAGGATTA GATAATCC GCTAATCC GGATTAAA GGATTAAC GGATTATA GGGGATTA TAATCCCA TGGATTAA |
| Publications: | Berger M.F, Badis G, Gehrke A.R, Talukder S, Philippakis A.A, Peña-Castillo L, Alleyne T.M, Mnaimneh S, Botvinnik O.B, Chan E.T, Khalid F, Zhang W, Newburger D, Jaeger S.A, Morris Q.D, Bulyk M.L, Hughes T.R. Variation in homeodomain DNA binding revealed by high-resolution analysis of sequence preferences. Cell 133:1266-76 (2008). [Pubmed] |
| Related annotations: | PaperBLAST |
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These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.