DNA Binding Site

Accessions: ATTAATCC (UniPROBE 20160601), MA0077.2.2 (JASPAR 2024)
Organisms: Mus musculus, Saccharomyces cerevisiae, Drosophila melanogaster, Homo sapiens
Libraries: UniPROBE 20160601 1, JASPAR 2024 2
1 Hume MA, Barrera LA, Gisselbrecht SS, Bulyk ML. UniPROBE, update 2015: new tools and content for the online database of protein-binding microarray data on protein-DNA interactions. Nucleic Acids Res : (2015). [Pubmed]
2 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed]
Length: 8
Sequence: ATTAATCC
Type: Heterodimer
Binding TFs: P48436 (HMG (high mobility group) box, Domain of unknown function (DUF1898), Sox developmental protein N terminal )
UP00474A (Fungal Zn(2)-Cys(6) binuclear cluster domain)
UP00216A (Homeobox domain)
UP00109A (Homeobox domain, Homeobox KN domain)
UP00111A (Homeobox domain)
UP00112A (Homeobox domain)
UP00125A (Homeobox domain)
UP00143A (Homeobox domain)
UP00153A (Homeobox domain)
UP00160A (Homeobox domain)
UP00176A (Homeobox domain)
UP00229A (Homeobox domain)
UP00239A (Homeobox domain)
UP00265A (Homeobox domain)
UP00267A (Homeobox domain)
UP00288A (Fungal Zn(2)-Cys(6) binuclear cluster domain)
UP00208A (Homeobox domain)
UP00508A (Homeobox domain)
UP00586B (Homeobox domain)
UP00586D (Homeobox domain)
UP00586E (Homeobox domain)
UP00615A / UP00615E (Homeobox domain)
UP00615B (Homeobox domain)
UP00615C (Homeobox domain)
P48436
Binding Motifs: UP00109A_1 awAArcGGATTAwhg
UP00111A_1 wdrwmmGGATTArkbww
UP00112A_1 aawmryTAATCCsytwv
UP00125A_1 kkwrrGGATTAAthrwy
UP00143A_1 rrmrGGGATTAAtyrtc
UP00153A_1 tkrrrGGGATTAAmaah
UP00160A_1 wbrgrGGGATTAAcwmh
UP00176A_1 ykwwGsGGATTArCck
UP00208A_1 wdrrGGGATTAAwTywm
UP00216A_1 ttarGGGGATTAAcwwy
UP00229A_1 dgwrgGGATTAAtwtwy
UP00239A_1 wkrgGGGGATTAAmwat
UP00265A_1 rggGGGATTAgCtrsc
UP00267A_1 kdwrgGGATTAAtydtc
UP00288A_1 hwcykyCGGAwaAAyttkmr
UP00208A_2 arragGGATTAAwTrwm
UP00474A_1 wmrswatcCGGAwmAWytywakt
UP00508A_1 wcctrrvGGGATTAAktrtcms
UP00586B_1 wmaawyrcTAATCCscttwwwr
UP00586D_1 twwwawsGGATAATCCchtywmm
UP00586E_1 cwgwwtAytsGGATTArgwrwv
UP00615A_1 kyysdtrgGGATTAAtwrkacs
UP00615A_2 kkkcwwtyTAATCCcyykmawm
UP00615B_1 wkwraaaAgGGATTArTagtrrr
UP00615B_2 khysrwrrGGATTAAtwrkaCs
UP00615C_1 mcgtmywATTAATCCyyhwrar
UP00615C_2 gykwaaAcGGATTAaTmwtgmvw
UP00615E_1 kwtkmrrkGGATTArawwkaamt
MA0077.2 CyATTGTT
Publications: Berger M.F, Badis G, Gehrke A.R, Talukder S, Philippakis A.A, Peña-Castillo L, Alleyne T.M, Mnaimneh S, Botvinnik O.B, Chan E.T, Khalid F, Zhang W, Newburger D, Jaeger S.A, Morris Q.D, Bulyk M.L, Hughes T.R. Variation in homeodomain DNA binding revealed by high-resolution analysis of sequence preferences. Cell 133:1266-76 (2008). [Pubmed]

Mertin S., McDowall S. G., Harley V. R. The DNA-binding specificity of SOX9 and other SOX proteins. Nucleic Acids Res. 27:1359-1364 (1999). [Pubmed]

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These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.