Transcription Factor
| Accessions: | UP00090A (UniPROBE 20160601), UP00407A (UniPROBE 20160601) |
| Names: | E74-like factor 3, Elf3, ESE-1, ESX, jen |
| Organisms: | Mus musculus |
| Libraries: | UniPROBE 20160601 1 1 Hume MA, Barrera LA, Gisselbrecht SS, Bulyk ML. UniPROBE, update 2015: new tools and content for the online database of protein-binding microarray data on protein-DNA interactions. Nucleic Acids Res : (2015). [Pubmed] |
| Uniprot: | Q3UPW2 |
| Description: | E74-like factor 3 |
| Length: | 143 |
| Pfam Domains: | 45-128 Ets-domain |
| Sequence: (in bold interface residues) | 1 RDGFPDYKKGEPKHGKRKRGRPRKLSKEYWDCLEGKKSKHAPRGTHLWEFIRDILIHPEL 60 61 NEGLMKWENRHEGVFKFLRSEAVAQLWGQKKKNSNMTYEKLSRAMRYYYKREILERVDGR 120 121 RLVYKFGKNSSGWKEEEVGESRN |
| Interface Residues: | 17, 19, 40, 99, 100, 102, 103, 104, 106, 107, 121 |
| 3D-footprint Homologues: | 7vru_C, 4uno_A, 3jtg_A, 1dux_F, 7jsa_J, 3zp5_A, 4mhg_A, 2stt_A, 8ee9_F, 4l18_B, 4lg0_B, 1yo5_C, 4bqa_A, 1awc_A, 4iri_A, 1bc8_C |
| Binding Motifs: | UP00090A_1 wwcmmGGAArTwa UP00407A_1 vhykwAyTTCCKgsttr UP00090A_2 gytcmaaaAAaAamydy |
| Binding Sites: | AACTTCCG AACTTCCT AAGGAAAT AATTTCCG AATTTCCT ACCCGGAA ACTTCCGC ACTTCCGG ACTTCCTG AGGAAGTA ATTTCCGC ATTTCCTG CACTTCCG CCCGGAAA CCCGGAAG CGGAAATA CGGAAGTA CTTCCGGC GGAAGTAA TTCCGGAA |
| Publications: | Badis G, Berger M.F, Philippakis A.A, Talukder S, Gehrke A.R, Jaeger S.A, Chan E.T, Metzler G, Vedenko A, Chen X, Kuznetsov H, Wang C.F, Coburn D, Newburger D.E, Morris Q, Hughes T.R, Bulyk M.L. Diversity and complexity in DNA recognition by transcription factors. Science (New York, N.Y.) 324:1720-3 (2009). [Pubmed] Wei G-H, Badis G, Berger MF, Kivioja T, Palin K, Enge M, Bonke M, Jolma A, Varjosalo M, Gehrke AR, Yan J, Talukder S, Turunen M, Taipale M, Stunnenberg HG, Ukkonen E, Hughes TR, Bulyk ML, Taipale J. Genome-wide analysis of ETS family DNA-binding in vitro and in vivo. The EMBO Journal. Epub 2010 Jun 1. doi:10.1038/emboj.2010.106 [Pubmed] |
| Related annotations: | PaperBLAST |
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These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.