Transcription Factor

Accessions: TGIF2LX (HT-SELEX2 May2017), TGIF2LY (HT-SELEX2 May2017)
Names: ENSG00000153779, TGIF2LX, ENSG00000176679, TGIF2LY
Organisms: Homo sapiens
Libraries: HT-SELEX2 May2017 1
1 Yin Y, Morgunova E, Jolma A, Kaasinen E, Sahu B, Khund-Sayeed S, Das PK, Kivioja T, Dave K, Zhong F, Nitta KR, Taipale M, Popov A, Ginno PA, Domcke S, Yan J, Schübeler D, Vinson C, Taipale J. Impact of cytosine methylation on DNA binding specificities of human transcription factors. Science : (2017). [Pubmed]
Notes: TF family: MEIS experiment: HT-SELEX Hamming distance: 1 cycle: 3, TF family: MEIS experiment: HT-SELEX Hamming distance: 1 cycle: 4, TF family: MEIS experiment: Methyl-HT-SELEX Hamming distance: 1 cycle: 3, TF family: MEIS experiment: Methyl-HT-SELEX Hamming distance: 1 cycle: 4, TF family: MEIS experiment: HT-SELEX Hamming distance: 1 cycle: 2, TF family: MEIS experiment: Methyl-HT-SELEX Hamming distance: 1 cycle: 2
Length: 114
Pfam Domains: 40-79 Homeobox KN domain
46-79 Homeobox domain
Sequence:
(in bold interface residues)
1 DTSIMSRNNADTGRVLALPEHKKKRKGNLPAESVKILRDWMYKHRFKAYPSEEEKQMLSE 60
61 KTNLSLLQISNWFINARRRILPDMLQQRRNDPIIGHKTGKDAHATHLQSTEASV
Interface Residues: 23, 25, 26, 27, 28, 67, 68, 70, 71, 74, 75, 76, 78, 79
3D-footprint Homologues: 6fqp_B, 1puf_B, 1au7_A, 2ld5_A, 1le8_A, 1k61_B, 7psx_B, 4xrm_B, 1zq3_P, 1le8_B, 2d5v_B, 1fjl_B, 6fqq_E, 1mnm_C
Binding Motifs: TGIF2LX_2 TGACAgcTGTCA
TGIF2LX_4 TGACAgcTGTCA
TGIF2LX_methyl_1 TGACAscTGTCA
TGIF2LX_methyl_3 TGACAgcTGTCA
TGIF2LY_2 TGACAgcTGTCA
TGIF2LY_methyl_1 tGACAgsTGTCa
Related annotations: PaperBLAST

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These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.