DNA Binding Motif
| Accessions: | TGIF2LY_2 (HT-SELEX2 May2017), MA1572.1 (JASPAR 2024) |
| Names: | TGIF2LY |
| Organisms: | Homo sapiens |
| Libraries: | HT-SELEX2 May2017 1, JASPAR 2024 2 1 Yin Y, Morgunova E, Jolma A, Kaasinen E, Sahu B, Khund-Sayeed S, Das PK, Kivioja T, Dave K, Zhong F, Nitta KR, Taipale M, Popov A, Ginno PA, Domcke S, Yan J, Schübeler D, Vinson C, Taipale J. Impact of cytosine methylation on DNA binding specificities of human transcription factors. Science : (2017). [Pubmed] 2 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed] |
| Notes: | HT-SELEX |
| Length: | 12 |
| Consensus: | TGACAgcTGTCA |
| Weblogo: |  |
| PSSM: | P0 A C G T 01 736 836 415 5209 T 02 162 270 5209 104 G 03 5209 163 349 1197 A 04 123 5209 66 144 C 05 5209 37 833 110 A 06 130 1267 2794 1018 g 07 1033 2850 1188 138 c 08 140 848 73 5209 T 09 175 61 5209 121 G 10 1084 371 145 5209 T 11 135 5209 259 172 C 12 5209 362 807 679 A |
| Type: | Heterodimer |
| Binding TFs: | TGIF2LY (Homeobox domain, Homeobox KN domain) Q8IUE0 (Homeobox domain, Homeobox KN domain) Q8IUE0 |
| Publications: | Yin Y, Morgunova E, Jolma A, Kaasinen E, Sahu B, Khund-Sayeed S, Das PK, Kivioja T, Dave K, Zhong F, Nitta KR, Taipale M, Popov A, Ginno PA, Domcke S, Yan J, Schübeler D, Vinson C, Taipale J. Impact of cytosine methylation on DNA binding specificities of human transcription factors. Science : (2017). [Pubmed] Bertolino E., Reimund B., Wildt-Perinic D., Clerc R. G. A novel homeobox protein which recognizes a TGT core and functionally interferes with a retinoid-responsive motif. J. Biol. Chem. 270:31178-31188 (1995). [Pubmed] |
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