Transcription Factor
| Accessions: | UP00537A (UniPROBE 20160601) |
| Names: | anon-EST:CL2d4, CG4677, Dmel\CG4677, gfl, Lame duck, Lmd, minc |
| Organisms: | Drosophila melanogaster |
| Libraries: | UniPROBE 20160601 1 1 Hume MA, Barrera LA, Gisselbrecht SS, Bulyk ML. UniPROBE, update 2015: new tools and content for the online database of protein-binding microarray data on protein-DNA interactions. Nucleic Acids Res : (2015). [Pubmed] |
| Description: | Lame duck: Lame duck( Lmd ), a member of the Gli superfamily of transcription factors, is essential for the specification and differentiation of fusion- competent myoblasts. |
| Length: | 218 |
| Pfam Domains: | 86-112 Zinc-finger double domain 100-123 Zinc finger, C2H2 type 100-123 C2H2-type zinc finger 115-142 Zinc-finger double domain 129-153 Zinc finger, C2H2 type 131-153 C2H2-type zinc finger 159-183 C2H2-type zinc finger 159-183 Zinc finger, C2H2 type |
| Sequence: (in bold interface residues) | 1 NDVFAPPAESDPKPDSTCCDPEAEPENEVIPLICRWTGCDEEFPHQQAFVEHIEKCHVDV 60 61 RKGEDFSCFWLDCPRRYKPFNARYKLLIHMRVHSGEKPNKCPFPGCNKAFSRLENLKIHQ 120 121 RSHTGERPYGCQYKGCLKAFSNSSDRAKHQRTHYDTKPYACQLPGCTKRYTDPSSLRKHV 180 181 KNHALRNANGQLRRKSAGGASVPPSGPKKAAKTRRHSE |
| Interface Residues: | 45, 47, 48, 51, 71, 81, 82, 83, 84, 85, 86, 87, 88, 90, 91, 92, 94, 111, 112, 113, 114, 115, 117, 118, 141, 142, 143, 144, 145, 146, 147, 148, 149, 171, 172, 173, 174, 175, 176, 177, 178, 179 |
| 3D-footprint Homologues: | 6wmi_A, 5yel_A, 2kmk_A, 3uk3_C, 7n5w_A, 2lt7_A, 5ei9_F, 8ssq_A, 7w1m_H, 8ssu_A, 6ml4_A, 5v3j_F, 2gli_A, 5kkq_D, 1tf6_A, 2i13_A, 1ubd_C, 7eyi_G, 8h9h_G, 5k5i_A, 8gn3_A, 6e94_A, 7ysf_A, 2jpa_A, 6jnm_A, 8cuc_F, 1tf3_A, 7y3l_A, 1mey_C, 5und_A, 1f2i_J, 1g2f_F, 6blw_A, 6u9q_A, 4x9j_A, 1llm_D, 5kl3_A, 7y3m_I, 6a57_A, 5yj3_D, 2drp_D, 7txc_E, 2wbs_A, 4m9v_C |
| Binding Motifs: | UP00537A_1 raagccmCCskGGGGGGcyrays UP00537A_2 kymwtvyAGGgGGTmswkdtga |
| Binding Sites: | ACCCCCCA ACCCCCCC ACCCCCCG AGACCCCC AGGGGGTC CACCCCCC CAGGGGGG CCCCCCAC CCCCCCCA CCCCCCCC CCCCCCCG CCCCCCGC CCCCCCGG GACCCCCA GACCCCCC GCCCCCCC GGACCCCC GGCCCCCC GGGGGGTA GGGGGTCA |
| Publications: | Busser BW, Huang D, Rogacki KR, Lane EA, Shokri L, Ni T, Gamble CE, Gisselbrecht SS, Zhu J, Bulyk ML, Ovcharenko I, Michelson AM. Integrative analysis of the zinc finger transcription factor Lame duck in the Drosophila myogenic gene regulatory network. Proc Natl Acad Sci U S A 109:20768-73 (2012). [Pubmed] |
| Related annotations: | PaperBLAST |
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