DNA Binding Site

Accessions: CAGGGGGG (UniPROBE 20160601), MA1102.3.15 (JASPAR 2024)
Organisms: Mus musculus, Saccharomyces cerevisiae, Drosophila melanogaster, Homo sapiens
Libraries: UniPROBE 20160601 1, JASPAR 2024 2
1 Hume MA, Barrera LA, Gisselbrecht SS, Bulyk ML. UniPROBE, update 2015: new tools and content for the online database of protein-binding microarray data on protein-DNA interactions. Nucleic Acids Res : (2015). [Pubmed]
2 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed]
Length: 8
Sequence: CAGGGGGG
Type: Heterodimer
Binding TFs: UP00006A (Zinc finger, C2H2 type, Zinc-finger double-stranded RNA-binding, Zinc-finger of C2H2 type, Zinc-finger double domain, C2H2-type zinc finger)
UP00343A (Zinc finger, C2H2 type, Zinc-finger double domain, C2H2-type zinc finger)
UP00537A (Zinc finger, C2H2 type, Zinc-finger double domain, C2H2-type zinc finger)
UP00599B (Zinc finger, C2H2 type, Zinc-finger double domain, C2H2-type zinc finger)
Q8NI51 (Zinc finger, C2H2 type, Zinc-finger double domain, C2H2-type zinc finger)
Q8NI51
Binding Motifs: UP00006A_1 smCCCCCgGGGGggt
UP00343A_1 dwwttmCCCCTGAAyttkks
UP00006A_2 kwdCaCAGCAkGmsa
UP00537A_1 raagccmCCskGGGGGGcyrays
UP00537A_2 kymwtvyAGGgGGTmswkdtga
UP00599B_1 rtsmcsmmCCCCCCccacgysg
MA1102.3 CAGGGGGC
Publications: Badis G, Berger M.F, Philippakis A.A, Talukder S, Gehrke A.R, Jaeger S.A, Chan E.T, Metzler G, Vedenko A, Chen X, Kuznetsov H, Wang C.F, Coburn D, Newburger D.E, Morris Q, Hughes T.R, Bulyk M.L. Diversity and complexity in DNA recognition by transcription factors. Science (New York, N.Y.) 324:1720-3 (2009). [Pubmed]

Pugacheva EM, Rivero-Hinojosa S, Espinoza CA, Méndez-Catalá CF, Kang S, Suzuki T, Kosaka-Suzuki N, Robinson S, Nagarajan V, Ye Z, Boukaba A, Rasko JE, Strunnikov AV, Loukinov D, Ren B, Lobanenkov VV. Comparative analyses of CTCF and BORIS occupancies uncover two distinct classes of CTCF binding genomic regions. Genome Biol : (2015). [Pubmed]

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