Transcription Factor
| Accessions: | UP00295A (UniPROBE 20160601) |
| Names: | Not Available, Yrm1 |
| Organisms: | Saccharomyces cerevisiae |
| Libraries: | UniPROBE 20160601 1 1 Hume MA, Barrera LA, Gisselbrecht SS, Bulyk ML. UniPROBE, update 2015: new tools and content for the online database of protein-binding microarray data on protein-DNA interactions. Nucleic Acids Res : (2015). [Pubmed] |
| Uniprot: | Not Av |
| Description: | Zn2-Cys6 zinc-finger transcription factor that activates genes involved in multidrug resistance; paralog of Yrr1p, acting on an overlapping set of target genes |
| Length: | 117 |
| Pfam Domains: | 28-64 Fungal Zn(2)-Cys(6) binuclear cluster domain |
| Sequence: (in bold interface residues) | 1 SKRGSLQDRASPSEETVKKAQKRRKPIKSCAFCRKRKLRCDQQKPMCSTCKTRGRSGCLY 60 61 TEKFTHKIETKELFGSTPNIELLKRIEDLEKRLDDKELTEKDVALSTSPFRNPYANF |
| Interface Residues: | 36, 37, 38, 71, 73, 74 |
| 3D-footprint Homologues: | 1pyi_A, 1hwt_C, 7uik_T, 1zme_D, 1d66_B, 3coq_A, 6gys_C |
| Binding Motifs: | UP00295A_1 sayhmrCGGAaATaagdcggw |
| Binding Sites: | AAAGAAAG AACGGAAA AAGAAAAA AATCTCCG AATTTCCG ACGGAAAT ACGGAGAA AGGGGGAA ATATCCGC ATTTCCGC ATTTCCGG CGGAAATA CGGAGATA CGGATATA CGGGAATA GGAGATAA GGGAATAA GGGGGAAA GGAAATAC GGAATTAA |
| Publications: | *Zhu C, *Byers K, *McCord RP, Shi Z, Berger MF, Newburger D, Saulrieta K, Smith Z, Shah M, Radhakrishnan M, Philippakis AA, Hu Y, De Masi F, Pacek M, Rolfs A , Murthy TVS, LaBaer J, Bulyk ML. High-Resolution DNA Binding Specificity Analysis of Yeast Transcription Factors. Genome Research. Epub January 21, 2009, doi:10.1101/gr.090233.108 (*co-1st authors). [Pubmed] |
| Related annotations: | PaperBLAST |
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