DNA Binding Site

Accessions: 5yi2_C (3D-footprint 20231221), 5yi2_D (3D-footprint 20231221), 5yi2_G (3D-footprint 20231221), 5yi2_H (3D-footprint 20231221), 5yi2_K (3D-footprint 20231221), 5yi2_L (3D-footprint 20231221), 5yi3_K (3D-footprint 20231221), 5yi3_L (3D-footprint 20231221), 5yi3_O (3D-footprint 20231221), 5yi3_P (3D-footprint 20231221)
Organisms: Lactococcus lactis, Lactococcus lactis subsp. lactis (strain IL1403)
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Length: 16
Sequence: TGTTAACTAGTTAACA
Type: Heterodimer
Binding TFs: 5yi2_B / 5yi2_F / 5yi2_J (Bacterial regulatory protein, arsR family, MarR family, Iron dependent repressor, N-terminal DNA binding domain, TFIIE alpha subunit, Transcriptional regulator, MarR family, Winged helix-turn-helix DNA-binding, Winged helix DNA-binding domain)
5yi3_I (Bacterial regulatory protein, arsR family, MarR family, Iron dependent repressor, N-terminal DNA binding domain, TFIIE alpha subunit, Transcriptional regulator, MarR family, Winged helix-turn-helix DNA-binding, Winged helix DNA-binding domain)
5yi3_N (Bacterial regulatory protein, arsR family, MarR family, Iron dependent repressor, N-terminal DNA binding domain, TFIIE alpha subunit, Transcriptional regulator, MarR family, Winged helix-turn-helix DNA-binding, Winged helix DNA-binding domain)
Binding Motifs: 5yi3_I TTAACT
5yi2_AB TTaAAnAGTTAAA
5yi2_EF TtaACnAGTTAA
5yi2_IJ TwAACyrGTTAA
5yi2_J rGTtAA
5yi3_MN TTAACTnGTTaA
Publications: Zhu R, Song Y, Liu H, Yang Y, Wang S, Yi C, Chen PR. Allosteric histidine switch for regulation of intracellular zinc(II) fluctuation. Proc Natl Acad Sci U S A 114:13661-13666 (2017). [Pubmed]

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