Transcription Factor

Accessions: 5yi3_M (3D-footprint 20231221), 5yi3_N (3D-footprint 20231221)
Names: Q9CDU5_LACLA, Zinc transport transcriptional regulator
Organisms: Lactococcus lactis, Lactococcus lactis subsp. lactis (strain IL1403)
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Length: 144
Pfam Domains: 34-91 MarR family
34-89 MarR family
35-80 Winged helix-turn-helix DNA-binding
35-98 Winged helix DNA-binding domain
40-81 Bacterial regulatory protein, arsR family
40-83 Transcriptional regulator
41-80 Iron dependent repressor, N-terminal DNA binding domain
41-113 TFIIE alpha subunit
(in bold interface residues)
Interface Residues: 35, 37, 52, 62, 63, 64, 65, 67, 68, 69, 72, 89
3D-footprint Homologues: 4kdp_B, 7el3_B, 6c2s_C, 1z9c_A, 6jbx_A, 3q5f_A, 5yi2_J, 8c7s_A, 4aik_A, 5hlg_E, 3zpl_B
Binding Motifs: 5yi3_MN TTAACTnGTTaA
Binding Sites: 5yi3_O / 5yi3_P
Publications: Zhu R, Song Y, Liu H, Yang Y, Wang S, Yi C, Chen PR. Allosteric histidine switch for regulation of intracellular zinc(II) fluctuation. Proc Natl Acad Sci U S A 114:13661-13666 (2017). [Pubmed]
Related annotations: PaperBLAST

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