DNA Binding Motif

Accessions: 5yi3_MN (3D-footprint 20231221)
Names: Zinc transport transcriptional regulator
Organisms: Lactococcus lactis, Lactococcus lactis subsp. lactis (strain IL1403)
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Description: Structure of Lactococcus lactis ZitR, C30S mutant in complex with DNA
Length: 12
Consensus: TTAACTnGTTaA
Weblogo:
PSSM: P0 A C G T
01 0 0 0 96 T
02 0 0 0 96 T
03 75 10 3 8 A
04 96 0 0 0 A
05 0 96 0 0 C
06 10 6 10 70 T
07 24 24 24 24 n
08 8 10 68 10 G
09 0 0 0 96 T
10 8 10 10 68 T
11 58 12 13 13 a
12 96 0 0 0 A
Binding TFs: 5yi3_M / 5yi3_N (Bacterial regulatory protein, arsR family, MarR family, Iron dependent repressor, N-terminal DNA binding domain, TFIIE alpha subunit, Transcriptional regulator, MarR family, Winged helix-turn-helix DNA-binding, Winged helix DNA-binding domain)
Binding Sites: 5yi3_O / 5yi3_P
Publications: Zhu R, Song Y, Liu H, Yang Y, Wang S, Yi C, Chen PR. Allosteric histidine switch for regulation of intracellular zinc(II) fluctuation. Proc Natl Acad Sci U S A 114:13661-13666 (2017). [Pubmed]

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