DNA Binding Motif

						

			
Accessions: 5yi2_AB (3D-footprint 20231221)

			
Names: Zinc transport transcriptional regulator
Organisms: Lactococcus lactis, Lactococcus lactis subsp. lactis (strain IL1403)
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Description: Structure of Lactococcus lactis ZitR, wild type in complex with DNA
Length: 13
Consensus: TTaAAnAGTTAAA
Weblogo: 
PSSM: P0      A      C      G      T
01      0      0      0     96      T
02      2      2      2     90      T
03     61     14     13      8      a
04     96      0      0      0      A
05     84      8      2      2      A
06     24     24     24     24      n
07     69      8     14      5      A
08      0      0     96      0      G
09      0      0      0     96      T
10      2      2      5     87      T
11     93      0      0      3      A
12     69     11     14      2      A
13     93      0      1      2      A
Type: Heterodimer
Binding TFs: 5yi2_A (Bacterial regulatory protein, arsR family, MarR family, Iron dependent repressor, N-terminal DNA binding domain, TFIIE alpha subunit, Transcriptional regulator, MarR family, Winged helix-turn-helix DNA-binding, Winged helix DNA-binding domain)
5yi2_B (Bacterial regulatory protein, arsR family, MarR family, Iron dependent repressor, N-terminal DNA binding domain, TFIIE alpha subunit, Transcriptional regulator, MarR family, Winged helix-turn-helix DNA-binding, Winged helix DNA-binding domain)
Binding Sites: 5yi2_C / 5yi2_D
			
Publications: Zhu R, Song Y, Liu H, Yang Y, Wang S, Yi C, Chen PR. Allosteric histidine switch for regulation of intracellular zinc(II) fluctuation. Proc Natl Acad Sci U S A 114:13661-13666 (2017). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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