DNA Binding Motif

Accessions: UP00029A_1 (UniPROBE 20160601)
Names: GTF2D, GTF2D1, HDL4, MGC117320, MGC126054, MGC126055, SCA17, TATA sequence-binding protein, TATA-binding factor, TATA-box factor, TATA-box-binding protein, TBP, Transcription initiation factor TFIID TBP subunit
Organisms: Homo sapiens
Libraries: UniPROBE 20160601 1
1 Hume MA, Barrera LA, Gisselbrecht SS, Bulyk ML. UniPROBE, update 2015: new tools and content for the online database of protein-binding microarray data on protein-DNA interactions. Nucleic Acids Res : (2015). [Pubmed]
Length: 16
Consensus: yywwwwTATAwwwmta
Weblogo:
PSSM: P0 A C G T
01 0.22 0.27 0.22 0.29 y
02 0.12 0.40 0.12 0.35 y
03 0.29 0.23 0.12 0.35 w
04 0.38 0.10 0.11 0.41 w
05 0.27 0.04 0.02 0.67 w
06 0.65 0.01 0.01 0.34 w
07 0.08 0.01 0 0.91 T
08 0.77 0 0 0.23 A
09 0.23 0 0 0.77 T
10 0.91 0 0.01 0.08 A
11 0.34 0.01 0.01 0.65 w
12 0.67 0.02 0.04 0.27 w
13 0.47 0.11 0.10 0.32 w
14 0.37 0.29 0.10 0.24 m
15 0.20 0.13 0.22 0.45 t
16 0.35 0.22 0.23 0.20 a
Binding TFs: UP00029A (Transcription factor TFIID (or TATA-binding protein, TBP))
Binding Sites: AAATATAT
AATATATA
AATATATT
ATATAAAT
ATATATAC
ATATATAG
ATATATAT
ATATATTA
ATATATTG
ATTATAAA
ATTATATA
CATATATA
CTTATATA
GATATATA
TAAATATA
TATAAATA
TATATAAA
TATATATA
TATTTAAA
TTATATAA
Publications: Badis G, Berger M.F, Philippakis A.A, Talukder S, Gehrke A.R, Jaeger S.A, Chan E.T, Metzler G, Vedenko A, Chen X, Kuznetsov H, Wang C.F, Coburn D, Newburger D.E, Morris Q, Hughes T.R, Bulyk M.L. Diversity and complexity in DNA recognition by transcription factors. Science (New York, N.Y.) 324:1720-3 (2009). [Pubmed]

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