DNA Binding Site
| Accessions: | TTATATAA (UniPROBE 20160601), PF0026.1.13 (JASPAR 2024), PF0026.1.9 (JASPAR 2024), MA1702.2.14 (JASPAR 2024), MA1702.2.15 (JASPAR 2024), MA1702.2.8 (JASPAR 2024), MA1702.2.9 (JASPAR 2024) |
| Organisms: | Homo sapiens, Saccharomyces cerevisiae, Plasmodium falciparum, Drosophila melanogaster |
| Libraries: | UniPROBE 20160601 1, JASPAR 2024 2 1 Hume MA, Barrera LA, Gisselbrecht SS, Bulyk ML. UniPROBE, update 2015: new tools and content for the online database of protein-binding microarray data on protein-DNA interactions. Nucleic Acids Res : (2015). [Pubmed] 2 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed] |
| Length: | 8 |
| Sequence: | TTATATAA |
| Type: | Heterodimer |
| Binding TFs: | UP00337A (Transcription factor TFIID (or TATA-binding protein, TBP)) UP00453A (bZIP transcription factor, Transcription factor PAP1) UP00454A (bZIP transcription factor) UP00473A (bZIP transcription factor) UP00352A (HMG (high mobility group) box, Domain of unknown function (DUF1898)) UP00325A (HMG (high mobility group) box, Domain of unknown function (DUF1898)) UP00029A (Transcription factor TFIID (or TATA-binding protein, TBP)) UP00441A (AP2 domain) UP00595D (Homeobox domain) Q24217 (bZIP transcription factor, Basic region leucine zipper) Q24217 |
| Binding Motifs: | UP00029A_1 yywwwwTATAwwwmta UP00325A_1 yttwyywwTATAwwwwrkdv UP00337A_1 vwhtaGrwATATATAtwsrwd UP00352A_1 mtkwhywmTATATAawwwwrh UP00029A_2 ccswtwwaasskabc UP00441A_1 mwwGmrwTWTATAWAdwmwkyC UP00453A_1 / UP00453A_2 ttswwwgATTAsTAATmdwavwr UP00453A_3 ATTACGTAA UP00454A_1 whkktgmTTACGTAAkmycswk UP00473A_1 / UP00473A_2 gsmmamtATTACGTAAtgsmryc UP00473A_3 ATTAcTAAT UP00595D_1 dkwdwwATrTATAtATartrdv PF0026.1 TTAyrTAA MA1702.2 TTATGYAA |
| Publications: | Badis G, Berger M.F, Philippakis A.A, Talukder S, Gehrke A.R, Jaeger S.A, Chan E.T, Metzler G, Vedenko A, Chen X, Kuznetsov H, Wang C.F, Coburn D, Newburger D.E, Morris Q, Hughes T.R, Bulyk M.L. Diversity and complexity in DNA recognition by transcription factors. Science (New York, N.Y.) 324:1720-3 (2009). [Pubmed] Xie X, Lu J, Kulbokas E.J, Golub T.R, Mootha V, Lindblad-Toh K, Lander E.S, Kellis M. Systematic discovery of regulatory motifs in human promoters and 3' UTRs by comparison of several mammals. Nature 434:338-45 (2005). [Pubmed] Nitta KR, Jolma A, Yin Y, Morgunova E, Kivioja T, Akhtar J, Hens K, Toivonen J, Deplancke B, Furlong EE, Taipale J. Conservation of transcription factor binding specificities across 600 million years of bilateria evolution. Elife : (2015). [Pubmed] |
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