DNA Binding Motif

Accessions: UP00109A_1 (UniPROBE 20160601)
Names: Not Available, Obox6, oocyte specific homeobox 6
Organisms: Mus musculus
Libraries: UniPROBE 20160601 1
1 Hume MA, Barrera LA, Gisselbrecht SS, Bulyk ML. UniPROBE, update 2015: new tools and content for the online database of protein-binding microarray data on protein-DNA interactions. Nucleic Acids Res : (2015). [Pubmed]
Length: 15
Consensus: awAArcGGATTAwhg
Weblogo:
PSSM: P0 A C G T
01 0.51 0.24 0.11 0.14 a
02 0.30 0.21 0.20 0.29 w
03 0.69 0.04 0.14 0.13 A
04 0.68 0.09 0.04 0.19 A
05 0.35 0.12 0.35 0.19 r
06 0.14 0.61 0.19 0.06 c
07 0.04 0 0.96 0 G
08 0 0 0.98 0.01 G
09 0.97 0.03 0 0 A
10 0 0 0 0.99 T
11 0.01 0.01 0 0.98 T
12 0.97 0 0 0.03 A
13 0.44 0.02 0.08 0.46 w
14 0.25 0.34 0.05 0.35 h
15 0.12 0.23 0.46 0.19 g
Binding TFs: UP00109A (Homeobox domain, Homeobox KN domain)
Binding Sites: AATAATCC
AGGATTAA
AGGATTAT
AGGGATTA
ATAATCCA
ATAATCCC
ATAATCCG
ATTAATCC
CATAATCC
CCGGATTA
CGGATTAA
GAGGATTA
GATAATCC
GCGGATTA
GGATTAAA
GGATTAAC
GGATTATA
GGGATTAA
GGGGATTA
TAATCCGA
Publications: Berger M.F, Badis G, Gehrke A.R, Talukder S, Philippakis A.A, Peña-Castillo L, Alleyne T.M, Mnaimneh S, Botvinnik O.B, Chan E.T, Khalid F, Zhang W, Newburger D, Jaeger S.A, Morris Q.D, Bulyk M.L, Hughes T.R. Variation in homeodomain DNA binding revealed by high-resolution analysis of sequence preferences. Cell 133:1266-76 (2008). [Pubmed]

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