DNA Binding Motif
| Accessions: | MA0830.3 (JASPAR 2024) |
| Names: | TCF4 |
| Organisms: | Homo sapiens |
| Libraries: | JASPAR 2024 1 1 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed] |
| Notes: | ChIP-seq |
| Length: | 8 |
| Consensus: | gCACCTGc |
| Weblogo: |  |
| PSSM: | P0 A C G T 01 4168 5062 18498 1737 g 02 243 28686 321 215 C 03 27023 635 1295 512 A 04 216 26765 1733 751 C 05 356 27724 1197 188 C 06 372 1016 679 27398 T 07 251 540 28432 242 G 08 1694 18935 5281 3555 c |
| Type: | Heterodimer |
| Binding TFs: | P15884 (Helix-loop-helix DNA-binding domain) P15884 |
| Binding Sites: | MA0830.3.14 / MA0830.3.16 / MA0830.3.18 MA0830.3.4 MA0830.3.5 MA0830.3.8 MA0830.3.1 MA0830.3.11 / MA0830.3.12 / MA0830.3.13 / MA0830.3.19 MA0830.3.6 MA0830.3.15 MA0830.3.2 MA0830.3.10 MA0830.3.17 MA0830.3.20 MA0830.3.3 MA0830.3.7 MA0830.3.9 |
| Publications: | Yang J, Horton JR, Li J, Huang Y, Zhang X, Blumenthal RM, Cheng X. Structural basis for preferential binding of human TCF4 to DNA containing 5-carboxylcytosine. Nucleic Acids Res 47:8375-8387 (2019). [Pubmed] |
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