Transcription Factor

Accessions: P15884 (JASPAR 2024)
Names: bHLHb19, Class B basic helix-loop-helix protein 19, Immunoglobulin transcription factor 2, ITF-2, ITF2_HUMAN, SEF-2, SL3-3 enhancer factor 2, TCF-4, Transcription factor 4
Organisms: Homo sapiens
Libraries: JASPAR 2024 1
1 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed]
Uniprot: P15884
Length:
Binding Motifs: MA0830.1 yrCACCTGbw
MA0830.2 cggCACCTGccss
MA0830.3 gCACCTGc
Binding Sites: MA0830.3.14 / MA0830.3.16 / MA0830.3.18
MA0830.3.4
MA0830.3.5
MA0830.3.8
MA0830.3.1
MA0830.3.11 / MA0830.3.12 / MA0830.3.13 / MA0830.3.19
MA0830.2.10 / MA0830.2.5
MA0830.2.1
MA0830.2.2
MA0830.2.4 / MA0830.2.5
MA0830.2.11 / MA0830.2.6
MA0830.2.12 / MA0830.2.7
MA0830.2.13 / MA0830.2.8
MA0830.2.10 / MA0830.2.14
MA0830.2.15
MA0830.2.16
MA0830.2.17
MA0830.2.18
MA0830.2.19
MA0830.2.11 / MA0830.2.20
MA0830.2.3
MA0830.2.3 / MA0830.2.4
MA0830.2.6
MA0830.2.7
MA0830.2.8
MA0830.2.9
MA0830.2.14
MA0830.2.18
MA0830.2.12
MA0830.2.13
MA0830.2.15
MA0830.2.16
MA0830.2.17
MA0830.2.19
MA0830.2.20
MA0830.2.9
MA0830.3.6
MA0830.3.15
MA0830.3.2
MA0830.3.10
MA0830.3.17
MA0830.3.20
MA0830.3.3
MA0830.3.7
MA0830.3.9
Publications: Kophengnavong T, Michnowicz J.E, Blackwell T.K. Establishment of distinct MyoD, E2A, and twist DNA binding specificities by different basic region-DNA conformations. Molecular and cellular biology 20:261-72 (2000). [Pubmed]

Yang J, Horton JR, Li J, Huang Y, Zhang X, Blumenthal RM, Cheng X. Structural basis for preferential binding of human TCF4 to DNA containing 5-carboxylcytosine. Nucleic Acids Res 47:8375-8387 (2019). [Pubmed]
Related annotations: PaperBLAST

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