Transcription Factor
| Accessions: | UP00418A (UniPROBE 20160601) |
| Names: | AW123102, AW557856, ETS translocation variant 6, ets variant gene 6 (TEL oncogene), ETS-related protein Tel1, Etv6, Transcription factor ETV6, translocation-ets-leukemia |
| Organisms: | Mus musculus |
| Libraries: | UniPROBE 20160601 1 1 Hume MA, Barrera LA, Gisselbrecht SS, Bulyk ML. UniPROBE, update 2015: new tools and content for the online database of protein-binding microarray data on protein-DNA interactions. Nucleic Acids Res : (2015). [Pubmed] |
| Uniprot: | Q3U037 |
| Description: | ets variant gene 6 (TEL oncogene): transcription factor ETV6 |
| Length: | 117 |
| Pfam Domains: | 18-99 Ets-domain |
| Sequence: (in bold interface residues) | 1 SPPEEHAMPIGRIADCRLLWDYVYQLLSDSRYENFIRWEDKESKIFRIVDPNGLARLWGN 60 61 HKNRTNMTYEKMSRALRHYYKLNIIRKEPGQRLLFRFMKTPDEIMSGRTDRLEHLES |
| Interface Residues: | 30, 64, 70, 71, 73, 74, 75, 77, 78, 92 |
| 3D-footprint Homologues: | 3k59_A, 2stt_A, 8ee9_F, 4mhg_A, 3jtg_A, 1dux_F, 4uno_A, 7jsa_J, 3zp5_A, 4lg0_B, 4bqa_A, 1bc8_C, 4iri_A, 4l18_B, 1yo5_C, 1awc_A |
| Binding Motifs: | UP00418A_1 dcmktAYTTCCGGytts |
| Binding Sites: | AACTTCCG ACCCGGAA ACCGGAAA ACCGGAAG ACTTCCGA ACTTCCGC ACTTCCTG AGGAAGTA ATTTCCGG CACTTCCG CCCGGAAA CCCGGAAG CCGGAAAC CCGGAAGC CGGAAATA CGGAAGTA CGGAAGTC CTTCCGGA GGAAGTAA TTCCGGAA |
| Publications: | Wei G-H, Badis G, Berger MF, Kivioja T, Palin K, Enge M, Bonke M, Jolma A, Varjosalo M, Gehrke AR, Yan J, Talukder S, Turunen M, Taipale M, Stunnenberg HG, Ukkonen E, Hughes TR, Bulyk ML, Taipale J. Genome-wide analysis of ETS family DNA-binding in vitro and in vivo. The EMBO Journal. Epub 2010 Jun 1. doi:10.1038/emboj.2010.106 [Pubmed] |
| Related annotations: | PaperBLAST |
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