DNA Binding Motif

Accessions: UP00418A_1 (UniPROBE 20160601)
Names: AW123102, AW557856, ETS translocation variant 6, ets variant gene 6 (TEL oncogene), ETS-related protein Tel1, Etv6, Transcription factor ETV6, translocation-ets-leukemia
Organisms: Mus musculus
Libraries: UniPROBE 20160601 1
1 Hume MA, Barrera LA, Gisselbrecht SS, Bulyk ML. UniPROBE, update 2015: new tools and content for the online database of protein-binding microarray data on protein-DNA interactions. Nucleic Acids Res : (2015). [Pubmed]
Length: 17
Consensus: dcmktAYTTCCGGytts
Weblogo:
PSSM: P0 A C G T
01 0.35 0.07 0.30 0.28 d
02 0.21 0.41 0.23 0.15 c
03 0.28 0.38 0.16 0.18 m
04 0.18 0.18 0.34 0.30 k
05 0.11 0.20 0.06 0.63 t
06 0.88 0 0.10 0.01 A
07 0 0.70 0.01 0.29 Y
08 0.01 0 0 0.98 T
09 0 0 0 0.99 T
10 0 0.99 0 0 C
11 0 0.99 0 0.01 C
12 0.01 0.01 0.94 0.04 G
13 0.02 0.20 0.76 0.02 G
14 0.23 0.27 0.12 0.38 y
15 0.23 0.09 0.03 0.64 t
16 0.19 0.18 0.18 0.45 t
17 0.15 0.29 0.34 0.22 s
Binding TFs: UP00418A (Ets-domain)
Binding Sites: AACTTCCG
ACCCGGAA
ACCGGAAA
ACCGGAAG
ACTTCCGA
ACTTCCGC
ACTTCCTG
AGGAAGTA
ATTTCCGG
CACTTCCG
CCCGGAAA
CCCGGAAG
CCGGAAAC
CCGGAAGC
CGGAAATA
CGGAAGTA
CGGAAGTC
CTTCCGGA
GGAAGTAA
TTCCGGAA
Publications: Wei G-H, Badis G, Berger MF, Kivioja T, Palin K, Enge M, Bonke M, Jolma A, Varjosalo M, Gehrke AR, Yan J, Talukder S, Turunen M, Taipale M, Stunnenberg HG, Ukkonen E, Hughes TR, Bulyk ML, Taipale J. Genome-wide analysis of ETS family DNA-binding in vitro and in vivo. The EMBO Journal. Epub 2010 Jun 1. doi:10.1038/emboj.2010.106 [Pubmed]

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