Transcription Factor
| Accessions: | UP00195A (UniPROBE 20160601) |
| Names: | Homeobox protein SIX3, Sine oculis homeobox homolog 3, sine oculis-related homeobox 3 homolog (Drosophila), Six3, Six3a, Six3alpha, Six3b, Six3beta |
| Organisms: | Mus musculus |
| Libraries: | UniPROBE 20160601 1 1 Hume MA, Barrera LA, Gisselbrecht SS, Bulyk ML. UniPROBE, update 2015: new tools and content for the online database of protein-binding microarray data on protein-DNA interactions. Nucleic Acids Res : (2015). [Pubmed] |
| Uniprot: | Q62233 |
| Description: | sine oculis-related homeobox 3 homolog (Drosophila): Mus musculus sine oculis-related homeobox 3 homolog (Drosophila) (Six3), mRNA. |
| Length: | 92 |
| Pfam Domains: | 20-71 Homeobox domain 35-69 Homeobox KN domain |
| Sequence: (in bold interface residues) | 1 RVRKKFPLPRTIWDGEQKTHCFKERTRSLLREWYLQDPYPNPSKKRELAQATGLTPTQVG 60 61 NWFKNRRQRDRAAAAKNRLQHQAIGPSGMRSL |
| Interface Residues: | 10, 16, 18, 19, 20, 21, 57, 58, 60, 61, 64, 65, 68, 69, 71, 72 |
| 3D-footprint Homologues: | 4xrs_G, 5zfz_A, 2lkx_A, 2r5y_A, 3l1p_A, 1k61_B, 1le8_B, 1mnm_C, 5jlw_D, 2ld5_A, 7q3o_C, 2h8r_B, 1ic8_B, 7xrc_C, 1le8_A, 1ig7_A, 2xsd_C, 1e3o_C, 1au7_A, 4j19_B, 3a01_E, 2h1k_B, 6fqp_B, 1fjl_B, 5flv_I, 3lnq_A, 1puf_B, 5zjt_E, 1b72_A, 4qtr_D, 3cmy_A, 1nk2_P, 6fqq_E, 5hod_A, 3rkq_B, 1zq3_P, 6a8r_A, 1du0_A, 4xrm_B, 3d1n_M, 2hdd_A, 1o4x_A, 4cyc_A, 2d5v_B, 8g87_X, 6es3_K, 1puf_A, 7psx_B, 1jgg_B, 6m3d_C |
| Binding Motifs: | UP00195A_1 rAtrGGGTATCAywwwt |
| Binding Sites: | AGGGTATC AGGTATCA AGTGATAC ATGATACC ATGATATC ATGATATG CATGATAC CGGATATC CGGTATCA GATACCCC GATATATC GATATCAA GATATCAC GATATCCC GATGATAC GGATATCA GGTATCAA GGTATCAC TGATATCA GGTGATAC |
| Publications: | Berger M.F, Badis G, Gehrke A.R, Talukder S, Philippakis A.A, Peña-Castillo L, Alleyne T.M, Mnaimneh S, Botvinnik O.B, Chan E.T, Khalid F, Zhang W, Newburger D, Jaeger S.A, Morris Q.D, Bulyk M.L, Hughes T.R. Variation in homeodomain DNA binding revealed by high-resolution analysis of sequence preferences. Cell 133:1266-76 (2008). [Pubmed] |
| Related annotations: | PaperBLAST |
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These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.