Transcription Factor

Accessions: UP00239A (UniPROBE 20160601)
Names: Not Available, Obox2, oocyte specific homeobox 2
Organisms: Mus musculus
Libraries: UniPROBE 20160601 1
1 Hume MA, Barrera LA, Gisselbrecht SS, Bulyk ML. UniPROBE, update 2015: new tools and content for the online database of protein-binding microarray data on protein-DNA interactions. Nucleic Acids Res : (2015). [Pubmed]
Uniprot: Q8VHG7
Description: oocyte specific homeobox 2
Length: 93
Pfam Domains: 17-73 Homeobox domain
Sequence:
(in bold interface residues)
1 DKYVNKQTSPMASRKFRKERTVYTKEEQGLLQKHFDECQYPNKKKIVELALSVGVTKREI 60
61 KIWFKNNRAKYRQMNLQNIEQALPESNGSSKAV
Interface Residues: 12, 14, 15, 16, 17, 18, 19, 20, 22, 24, 26, 28, 58, 59, 61, 62, 65, 66, 69, 70, 73
3D-footprint Homologues: 1mnm_C, 6x1j_A, 3cmy_A, 1ig7_A, 6a8r_A, 3d1n_M, 5zfz_A, 2h1k_B, 1puf_A, 1fjl_B, 1nk2_P, 1zq3_P, 2lkx_A, 6es3_K, 2ld5_A, 7q3o_C, 2hdd_A, 1b72_A, 5hod_A, 3rkq_B, 2r5y_A, 1puf_B, 2hos_A, 7psx_B, 5jlw_D, 4cyc_A, 1jgg_B, 4xrs_G, 4j19_B, 3a01_E, 6m3d_C, 1au7_A, 5flv_I, 3lnq_A, 5zjt_E, 2xsd_C, 1e3o_C, 1le8_A, 7xrc_C, 4qtr_D, 8g87_X, 4xrm_B, 1du0_A, 3l1p_A, 1o4x_A
Binding Motifs: UP00239A_1 wkrgGGGGATTAAmwat
Binding Sites: AATAATCC
AGATTAAA
AGGATTAA
AGGATTAT
AGGGATTA
ATAATCCA
ATAATCCC
ATTAATCC
ATTTAATC
CGGGATTA
CTAATCCC
CTTAATCC
GATAATCC
GATTAAAA
GCTAATCC
GGATTAAA
GGATTAAC
GGATTATA
GGGATTAA
TGGATTAA
Publications: Berger M.F, Badis G, Gehrke A.R, Talukder S, Philippakis A.A, Peña-Castillo L, Alleyne T.M, Mnaimneh S, Botvinnik O.B, Chan E.T, Khalid F, Zhang W, Newburger D, Jaeger S.A, Morris Q.D, Bulyk M.L, Hughes T.R. Variation in homeodomain DNA binding revealed by high-resolution analysis of sequence preferences. Cell 133:1266-76 (2008). [Pubmed]
Related annotations: PaperBLAST

Disclaimer and license

These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.