Transcription Factor

Accessions: UP00287A (UniPROBE 20160601)
Names: Gat1, MEP80, NIL1, Transcriptional regulatory protein GAT1, YFL021W
Organisms: Saccharomyces cerevisiae
Libraries: UniPROBE 20160601 1
1 Hume MA, Barrera LA, Gisselbrecht SS, Bulyk ML. UniPROBE, update 2015: new tools and content for the online database of protein-binding microarray data on protein-DNA interactions. Nucleic Acids Res : (2015). [Pubmed]
Uniprot: P43574
Description: Transcriptional activator of genes involved in nitrogen catabolite repression, member of the GATA family of DNA binding proteins; activity and localization regulated by nitrogen limitation and Ure2p
Length: 135
Pfam Domains: 51-84 GATA zinc finger
Sequence:
(in bold interface residues)
1 NPSPSIVKPGSRRNSSVRKKKPALKKIKSSTSVQSSATPPSNTSSNPDIKCSNCTTSTTP 60
61 LWRKDPKGLPLCNACGLFLKLHGVTRPLSLKTDIIKKRQRSSTKINNNITPPPSSSLNPG 120
121 AAGKKKNYTASVAAS
Interface Residues: 60, 61, 63, 73, 77, 78, 81, 98, 100
3D-footprint Homologues: 1gat_A, 3dfx_B, 4gat_A, 3vd6_C
Binding Motifs: UP00287A_1 yyatytyCTTATCgsrddhh
Binding Sites: AAGATAAG
ACGATAAG
AGATAAGA
AGATAAGC
ATGATAAG
CCGATAAG
CCTTATCA
CCTTATCG
CGATAACG
CGATAAGA
CGATAAGC
CTCTTATC
CTGATAAG
CTTATCAA
CTTATCGC
CTTATCTA
GATAAGAA
GATAAGGA
GCTTATCA
TCTTATCA
Publications: *Zhu C, *Byers K, *McCord RP, Shi Z, Berger MF, Newburger D, Saulrieta K, Smith Z, Shah M, Radhakrishnan M, Philippakis AA, Hu Y, De Masi F, Pacek M, Rolfs A , Murthy TVS, LaBaer J, Bulyk ML. High-Resolution DNA Binding Specificity Analysis of Yeast Transcription Factors. Genome Research. Epub January 21, 2009, doi:10.1101/gr.090233.108 (*co-1st authors). [Pubmed]
Related annotations: PaperBLAST

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