DNA Binding Site

Accessions: TCTTATCA (UniPROBE 20160601), MA0037.5.13 (JASPAR 2024), MA0037.5.14 (JASPAR 2024), MA0037.5.5 (JASPAR 2024), MA1104.3.3 (JASPAR 2024), MA1104.3.9 (JASPAR 2024), MA1701.2.1 (JASPAR 2024), MA1701.2.11 (JASPAR 2024), MA1701.2.12 (JASPAR 2024), MA1701.2.15 (JASPAR 2024), MA1701.2.17 (JASPAR 2024), MA1701.2.2 (JASPAR 2024), MA1701.2.20 (JASPAR 2024), MA1701.2.4 (JASPAR 2024), MA1701.2.5 (JASPAR 2024), MA1970.2.16 (JASPAR 2024), MA1970.2.2 (JASPAR 2024)
Organisms: Mus musculus, Saccharomyces cerevisiae, Homo sapiens, Caenorhabditis elegans
Libraries: UniPROBE 20160601 1, JASPAR 2024 2
1 Hume MA, Barrera LA, Gisselbrecht SS, Bulyk ML. UniPROBE, update 2015: new tools and content for the online database of protein-binding microarray data on protein-DNA interactions. Nucleic Acids Res : (2015). [Pubmed]
2 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed]
Length: 8
Sequence: TCTTATCA
Type: Heterodimer
Binding TFs: UP00347A (GATA zinc finger)
P23772 (GATA zinc finger)
Q92908 (GATA zinc finger, GATA-type transcription activator, N-terminal )
UP00080A (GATA zinc finger)
UP00100A (GATA zinc finger)
UP00287A (GATA zinc finger)
UP00032A (GATA zinc finger)
Q10655 (GATA zinc finger)
Q9UHF7 (GATA zinc finger)
P23772
Q10655
Q92908
Q9UHF7
Binding Motifs: UP00032A_1 bkwdwakAGATAAGArwtdarg
UP00080A_1 wwwrcTGATAAGrrgat
UP00100A_1 wawmkwGATAAGarttr
UP00287A_1 yyatytyCTTATCgsrddhh
UP00347A_1 twvmrrCYGATAAGrrwkwh
UP00032A_2 ytwtrywGATtktATCrrbwhm
UP00080A_2 rmcmrAGATATCwgybk
UP00100A_2 gsgrCGATATCGsmgyd
MA0037.5 tCTTATCT
MA1104.3 TCTTATCT
MA1701.2 tCTTATCA
MA1970.2 TCTTATCT
Publications: Badis G, Berger M.F, Philippakis A.A, Talukder S, Gehrke A.R, Jaeger S.A, Chan E.T, Metzler G, Vedenko A, Chen X, Kuznetsov H, Wang C.F, Coburn D, Newburger D.E, Morris Q, Hughes T.R, Bulyk M.L. Diversity and complexity in DNA recognition by transcription factors. Science (New York, N.Y.) 324:1720-3 (2009). [Pubmed]

Merika M., Orkin S. H. DNA-binding specificity of GATA family transcription factors. Mol. Cell. Biol. 13:3999-4010 (1993). [Pubmed]

Shaw-White J. R., Bruno M. D., Whitsett J. A. GATA-6 activates transcription of thyroid transcription factor-1.. J. Biol. Chem. 274:2658-2664 (1999). [Pubmed]

Hawkins MG, McGhee JD. elt-2, a second GATA factor from the nematode Caenorhabditis elegans. J Biol Chem 270:14666-71 (1995). [Pubmed]

Serandour AA, Mohammed H, Miremadi A, Mulder KW, Carroll JS. TRPS1 regulates oestrogen receptor binding and histone acetylation at enhancers. Oncogene 37:5281-5291 (2018). [Pubmed]

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These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.